| Laser-assisted hatching of cryopreserved-thawed embryos by thinning one quarter of the zona. | |
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MedLine Citation:
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PMID: 17169177 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Laser-assisted hatching is little documented in the literature regarding its efficacy in cryopreserved-thawed (CT) embryo transfer cycles. The aim of the present study was to evaluate in a randomized manner the efficacy of thinning one quarter of the zona pellucida of CT embryos to a depth of 50-80% of the original thickness, via laser treatment (the qLZT-AH procedure), in improving implantation and pregnancy rates. Two populations were studied: population I, patients who had all their supernumerary embryos cryopreserved, regardless of their morphology, and population II, patients at risk of ovarian hyperstimulation syndrome who had all their embryos cryopreserved. Artificial and natural protocols were used for the embryo transfers. A total of 350 laser-thinned CT embryos were compared with 352 intact zona embryos. No difference in implantation or pregnancy rate was found after using qLZT-AH in either population. These findings suggest that qLZT-AH should not be routinely performed in cryopreserved embryo programmes. |
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Authors:
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Claudia Guilhermino Petersen; Ana Lucia Mauri; Ricardo Luiz Razera Baruffi; João Batista Alcântara Oliveira; Valeria Felipe; Fabiana Cagnoto Massaro; Jose Gonçalves Franco |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Reproductive biomedicine online Volume: 13 ISSN: 1472-6483 ISO Abbreviation: Reprod. Biomed. Online Publication Date: 2006 Nov |
Date Detail:
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Created Date: 2006-12-15 Completed Date: 2007-01-09 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 101122473 Medline TA: Reprod Biomed Online Country: England |
Other Details:
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Languages: eng Pagination: 668-75 Citation Subset: IM |
Affiliation:
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Centre for Human Reproduction Prof Franco Junior, Av. Prof. João Fiusa 689-CEP 14025-310, Ribeirão Preto, SP-Brazil. petersenclaudia@crh.com.br |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cryopreservation / methods Embryo Implantation* Embryo Transfer* Female Humans Laser Therapy* Pregnancy Sperm Injections, Intracytoplasmic / methods Zona Pellucida / ultrastructure* |
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