Document Detail


Laser ablation studies of the role of the Drosophila oocyte nucleus in pattern formation.
MedLine Citation:
PMID:  1925585     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Somatic and germline cells interact during oogenesis to establish the pattern axes of the Drosophila eggshell and embryo. The role of the oocyte nucleus in pattern formation was tested with the use of laser ablation. Ablation in stage 6 to 9 egg chambers caused partial or complete ventralization of the eggshell, phenotypes similar to those of eggs produced by gurken or torpedo females. Accumulation of vasa protein at the posterior pole of treated oocytes was also disrupted. Thus the oocyte nucleus is required as late as stage 9 for dorsoventral patterning within the follicle cells and for polar plasm assembly in the oocyte.
Authors:
D J Montell; H Keshishian; A C Spradling
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Science (New York, N.Y.)     Volume:  254     ISSN:  0036-8075     ISO Abbreviation:  Science     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1991-11-01     Completed Date:  1991-11-01     Revised Date:  2009-09-28    
Medline Journal Info:
Nlm Unique ID:  0404511     Medline TA:  Science     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  290-3     Citation Subset:  IM    
Affiliation:
Carnegie Institution of Washington, Baltimore, MD 21210.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Nucleus / physiology*
Cell Polarity / physiology
Drosophila / embryology*
Egg Shell
Genes
Laser Therapy
Microsurgery
Morphogenesis
Mutation
Oocytes / physiology*
Oogenesis
Grant Support
ID/Acronym/Agency:
//Howard Hughes Medical Institute

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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