Document Detail


Laser Raman spectroscopic study of specifically deuterated phospholipid bilayers.
MedLine Citation:
PMID:  7378385     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Raman spectra of 1,2-dimyristoyl-sn-glycero-3-phosphocholines specifically deuterated in the 2 chain at one of positions 3, 4, 6, 10, 12, and 14 have been obtained as a function of temperature. The frequencies of the CD2 vibrational stretching modes depend on the position of the labeled CD2 group, being maximum at position 3 of the acyl chain and then decreasing until they become constant beyond position 6. This frequency dependence is interpreted in terms of the inductive effect of the charge distribution of the acyl chain carboxyl group. In both gel and liquid-crystal phases, the Raman line widths depend on the position of the CD2 group, being minimum at position 6 and increasing toward both ends of the hydrocarbon chain. The width of the CD stretching bands abruptly increases at the phase transition temperature. The magnitude of the increase depends upon the position of the label, increasing almost linearly up to position 10 and then decreasing for positions 12 and 14. The spectra for the CD2 group at position at position 3 and the terminal CD3 group are almost the same in both phases. These results are interpreted in terms of the effects of hydrocarbon chain organization on the vibrational modes.
Authors:
R Bansil; J Day; M Meadows; D Rice; E Oldfield
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Biochemistry     Volume:  19     ISSN:  0006-2960     ISO Abbreviation:  Biochemistry     Publication Date:  1980 Apr 
Date Detail:
Created Date:  1980-08-25     Completed Date:  1980-08-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370623     Medline TA:  Biochemistry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1938-43     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Deuterium
Dimyristoylphosphatidylcholine
Lipid Bilayers*
Molecular Conformation
Myristic Acids
Phosphatidylcholines*
Spectrum Analysis, Raman
Chemical
Reg. No./Substance:
0/Lipid Bilayers; 0/Myristic Acids; 0/Phosphatidylcholines; 13699-48-4/Dimyristoylphosphatidylcholine; 7782-39-0/Deuterium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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