Document Detail


Laser Doppler measurement of cutaneous blood flow.
MedLine Citation:
PMID:  894068     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This work describes an instrument for the noninvasive measurement of cutaneous blood flow velocity. The system utilizes the Doppler shift of laser light backscattered from moving red blood cells in the cutaneous microcirculation, the shift being obtained by an optical heterodyning technique. Comparison is made between this technique and the 133xenon clearance technique in measuring cutaneous flow in the forearms of normal volunteers. Variations in flow were obtained by inducing different degrees of solar erythema with an ultraviolet sunlamp. A Y on X linear regression yielded a regression coefficient = 0.89 (p less than 0.001, n = 16) between the two methods. The laser Doppler method appear to represent a practical technique for clinical evaluation of cutaneous blood flow in any skin surface.
Authors:
G A Holloway; D W Watkins
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of investigative dermatology     Volume:  69     ISSN:  0022-202X     ISO Abbreviation:  J. Invest. Dermatol.     Publication Date:  1977 Sep 
Date Detail:
Created Date:  1977-10-28     Completed Date:  1977-10-28     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0426720     Medline TA:  J Invest Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  306-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Flow Velocity*
Doppler Effect*
Female
Humans
Lasers / diagnostic use*
Male
Microcirculation / physiology
Middle Aged
Physical Phenomena
Physics*
Skin / blood supply*
Sunburn / physiopathology
Xenon Radioisotopes / diagnostic use
Chemical
Reg. No./Substance:
0/Xenon Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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