| Laser Ablation ICP-MS Co-localization of Mercury and Immune Response in Fish. | |
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MedLine Citation:
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PMID: 21894892 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Mercury (Hg) contamination is a global issue with implications for both ecosystem and human health. In this study, we use a new approach to link Hg exposure to health effects in spotted gar (Lepisosteus oculatus) from Caddo Lake (TX/LA, USA). Previous field studies have reported elevated incidences of macrophage centers in liver, kidney, and spleen of fish with high concentrations of Hg. Macrophage centers are aggregates of specialized white blood cells that form as an immune response to tissue damage, and are considered a general biomarker of contaminant toxicity. We found elevated incidences of macrophage centers in liver of spotted gar and used a new technology for ecotoxicology studies, laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS), to co-localize aggregates and Hg deposits within the tissue architecture. We conclude that Hg compromises the health of spotted gar in our study and, perhaps, other fish exposed to elevated concentrations of Hg. |
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Authors:
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Benjamin D Barst; Amanda K Gevertz; Matthew M Chumchal; James D Smith; Thomas Rainwater; Paul Drevnick; Karista E Hudelson; Aaron Hart; Guido F Verbeck; Aaron Patrick Roberts |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-6 |
Journal Detail:
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Title: Environmental science & technology Volume: - ISSN: 1520-5851 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-7 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0213155 Medline TA: Environ Sci Technol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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