Document Detail

Laryngeal morbidity after tracheal intubation: the Endoflex(®) tube compared to conventional endotracheal intubation with stylet.
MedLine Citation:
PMID:  23379725     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Tracheal intubation may cause vocal fold damage. The trial was designed to assess laryngeal morbidity comparing the Endoflex(®) tube with a conventional endotracheal tube with stylet. We hypothesised that laryngeal morbidity within the first 24 h after extubation would be lower with the Endoflex tube than with the conventional endotracheal tube with stylet because of less rigidity.
METHODS: This randomised trial included 130 elective surgical patients scheduled for general anaesthesia with endotracheal intubation. Pre- and post-operative assessment of hoarseness, vocal fold pathology, and voice analysis using the Multidimensional Voice Program was performed. Induction of anaesthesia was standardised. After complete neuromuscular paralysis, intubation was done with an Endoflex tube or a conventional endotracheal tube with stylet.
RESULTS: Post-operative hoarseness was found in 45% with the Endoflex tube and 55% with the endotracheal tube with stylet at 24 h after extubation (P = 0.44). Post-operative vocal fold injury was present in 23% in the Endoflex tube group and in 36% in the endotracheal tube with stylet group (P = 0.13). The increase in shimmer, the voice analysis variable reflecting vocal fold oedema, was 0.5% in the Endoflex tube group and 2.5% in the endotracheal tube with stylet group (P = 0.02).
CONCLUSION: No significant difference was found in the incidence of hoarseness or vocal fold injury using the Endoflex tube. However, the statistically significant lower increase in the shimmer values in that group implies that the Endoflex may be associated with less laryngeal morbidity.
M K Sørensen; N Rasmussen; M S Kristensen; M Bøttger; B B Fredensborg; C M Hansen; L S Rasmussen
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2013-02-05
Journal Detail:
Title:  Acta anaesthesiologica Scandinavica     Volume:  57     ISSN:  1399-6576     ISO Abbreviation:  Acta Anaesthesiol Scand     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-10     Completed Date:  2013-10-24     Revised Date:  2014-01-31    
Medline Journal Info:
Nlm Unique ID:  0370270     Medline TA:  Acta Anaesthesiol Scand     Country:  England    
Other Details:
Languages:  eng     Pagination:  737-44     Citation Subset:  IM    
Copyright Information:
© 2013 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
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MeSH Terms
Airway Extubation / adverse effects
Anesthesia, Inhalation / instrumentation
Hoarseness / etiology
Intubation, Intratracheal / adverse effects*,  instrumentation*
Laryngeal Edema / etiology
Middle Aged
Postoperative Complications / etiology,  prevention & control*
Prospective Studies
Single-Blind Method
Surgical Procedures, Elective
Vocal Cords / injuries*
Voice Quality
Comment In:
Acta Anaesthesiol Scand. 2014 Jan;58(1):127   [PMID:  24004047 ]
Acta Anaesthesiol Scand. 2014 Jan;58(1):127-8   [PMID:  24134477 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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