Document Detail

Laryngeal glycogenic acanthosis presenting as leukoplakia.
MedLine Citation:
PMID:  9738816     Owner:  NLM     Status:  MEDLINE    
We report a case of an incidental finding of glycogenic acanthosis of the larynx on autopsy in a 79-year-old man who died of myocardial infarction. The lesion was grossly recognized as a white plaque (leukoplakia) on the subglottic compartment of the left side of the larynx. Histological sections revealed thickened squamous mucosa positive for abundant glycogen on periodic acid-Schiff staining. No epithelial dysplasia was noted. The patient had a history of smoking. This case represents the first report of glycogenic acanthosis involving the larynx. This benign condition should be added to the vast differential diagnosis of leukoplakia in this anatomical location.
B S Fyfe; F U Garcia
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of otolaryngology--head & neck surgery     Volume:  124     ISSN:  0886-4470     ISO Abbreviation:  Arch. Otolaryngol. Head Neck Surg.     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-09-29     Completed Date:  1998-09-29     Revised Date:  2006-03-28    
Medline Journal Info:
Nlm Unique ID:  8603209     Medline TA:  Arch Otolaryngol Head Neck Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1029-30     Citation Subset:  AIM; IM    
Department of Pathology and Laboratory Medicine, Allegheny University-Hahnemann, MCP-Hahnemann School of Medicine, Philadelphia, PA 19102-1192, USA.
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MeSH Terms
Diagnosis, Differential
Glycogen / analysis
Laryngeal Diseases / pathology*
Laryngeal Mucosa / chemistry,  pathology
Leukoplakia / pathology*
Reg. No./Substance:

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