| Laryngeal candidiasis. Report of seven cases and review of the literature. | |
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MedLine Citation:
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PMID: 6391443 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although infections due to Candida have become increasingly recognized in recent years, laryngeal candidiasis remains a poorly described and infrequently diagnosed manifestation of mucous membrane candidal infection. Seven cases of isolated laryngeal candidiasis (ILC) have been identified at our institution during the past eight years (one before and six after death). Clinical, laboratory, and histopathologic findings from those seven cases, as well as from 12 additional cases reported in the literature, are reviewed. When hoarseness and dysphagia occur in patients with significant underlying disease who are receiving broad-spectrum antimicrobic therapy, a diagnosis of ILC should be considered. The diagnostic procedure of choice is indirect laryngoscopy with specimens submitted for culture and histopathologic study. On confirmation of the diagnosis, amphotericin B is the recommended therapy. Early treatment may limit morbidity and prevent systemic candidal dissemination. |
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Authors:
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L S Tashjian; J E Peacock |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Archives of otolaryngology (Chicago, Ill. : 1960) Volume: 110 ISSN: 0003-9977 ISO Abbreviation: Arch Otolaryngol Publication Date: 1984 Dec |
Date Detail:
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Created Date: 1984-12-31 Completed Date: 1984-12-31 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0376526 Medline TA: Arch Otolaryngol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 806-9 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Amphotericin B / therapeutic use Candida albicans / isolation & purification Candidiasis / diagnosis*, drug therapy, etiology Child Female Humans Laryngeal Diseases / diagnosis*, drug therapy, etiology Laryngeal Mucosa / microbiology Leukemia, Myeloid / complications Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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1397-89-3/Amphotericin B |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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