Document Detail

Laryngeal aerodynamic analysis in assisting with the diagnosis of muscle tension dysphonia.
MedLine Citation:
PMID:  21550774     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE/HYPOTHESIS: To estimate the aerodynamic multiparameters for patients with muscular tension dysphonia (MTD) and evaluate voice aerodynamic analysis for assisting the diagnosis of this disorder.
STUDY DESIGN: A prospective study.
METHODS: Voice aerodynamic parameters, including subglottal pressure (SGP) level, glottal resistance (GR), mean airflow rate (MFR), and maximum phonation time (MPT), for 26 MTD patients and 27 normal adults were analyzed using receiver operating characteristics (ROC) analysis and multivariate logistic regression.
RESULTS: For male samples, MTD patients had higher SGP (P=0.001), higher GR (P=0.012), lower MFR (P=0.042), and shorter MPT (P=0.027), whereas for female samples, the difference between cases and controls was statistically significant only in SGP (P<0.001) and MPT (P<0.001). ROC analysis showed that the threshold of 8.175 cm H(2)O for SGP achieved a good classification for MTD, with an adequate sensitivity (76.9%) and the perfect specificity (100%). Finally, multivariate logistic regression established a credible model (with SGP and MPT as the predictors) for classifying MTD, with a 92.5% percentage correct.
CONCLUSIONS: This analysis indicates that aerodynamics evaluation could help the diagnosis of MTD patients, jointly with medical history scrutiny, physical examination, fibrolaryngoscopy, and/or videoendostroboscopy.
Yi-Qing Zheng; Bi-Ru Zhang; Wei-Yang Su; Jian Gong; Man-Qiong Yuan; Yuan-Lin Ding; Shao-Qi Rao
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-05-07
Journal Detail:
Title:  Journal of voice : official journal of the Voice Foundation     Volume:  26     ISSN:  1873-4588     ISO Abbreviation:  J Voice     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-03-12     Completed Date:  2012-07-10     Revised Date:  2013-05-02    
Medline Journal Info:
Nlm Unique ID:  8712262     Medline TA:  J Voice     Country:  United States    
Other Details:
Languages:  eng     Pagination:  177-81     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 The Voice Foundation. Published by Mosby, Inc. All rights reserved.
Department of Otorhinolaryngology/Head and Neck Surgery, Second Affiliated Hospital (Sun Yat-Sen Memorial Hospital), Sun Yat-Sen University, Guangzhou, China.
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MeSH Terms
Case-Control Studies
Dysphonia / diagnosis*,  physiopathology
Larynx / physiopathology*
Logistic Models
Middle Aged
Muscle Tonus*
ROC Curve
Speech Acoustics
Young Adult

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