Document Detail

Larvicidal and pupicidal activity of spinosad against the malarial vector Anopheles stephensi.
MedLine Citation:
PMID:  21914537     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: To investigate the larvicidal and pupicidal activity of spinosad against Anopheles stephensi Listen.
METHODS: Spinosad from the actinomycete, Saccharopolyspora spinosa was tested against Anopheles stephensi at different concentrations (0.01, 0.02, 0.04, 0.06 and 0.08 ppm.), and against first to fourth instar larvae and pupae.
RESULTS: The larval mortality ranged from 36.1±1.7 in (0.01 ppm) to 79.3±1.8 (0.08 ppm) the first instar larva. The LC(50) and LC(90) values of first, second, third and fourth instar larva were 0.001, 0.031, 0.034, 0.036 and 0.0113, 0.102, 0.111, 0.113, respectively. The pupal mortality ranged from 33.0±2.0 (0.01 ppm) to 80.0±0.9 (0.08 ppm). The LC(50) and LC(90) values were 0.028 and 0.1020, respectively. The reduction percentage of Anopheles larvae was 82.7%, 91.4% and 96.0% after 24, 48, 72 hours, respectively, while more than 80% reduction was observed after 3 weeks.
CONCLUSIONS: In the present study spinosad effectively caused mortality of mosquito larvae in both the laboratory and field trial. It is predicted that spinosad is likely to be an effective larvicide for treatment of mosquito breeding sites.
Kolanthasamy Prabhu; Kadarkarai Murugan; Arjunan Nareshkumar; Subramanian Bragadeeswaran
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Asian Pacific journal of tropical medicine     Volume:  4     ISSN:  1995-7645     ISO Abbreviation:  Asian Pac J Trop Med     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-09-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101533720     Medline TA:  Asian Pac J Trop Med     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  610-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Hainan Medical College. Published by Elsevier B.V. All rights reserved.
Centre of Advanced Study in Marine Biology, Faculty of Marine Sciences, Annamalai University, Parangipettai-608 502.
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