Document Detail

Larvicidal efficacy of nitenpyram on the treatment of myiasis caused by Cochliomyia hominivorax (Diptera: Calliphoridae) in dogs.
MedLine Citation:
PMID:  20638181     Owner:  NLM     Status:  MEDLINE    
The purpose of our study was to evaluate the larvicidal efficacy of nitenpyram for the treatment of screwworm myiasis caused by Cochliomyia hominivorax in naturally infested dogs. Seven Beagle dogs presenting with myiasis were treated with nitenpyram twice at an interval of 6 h. The animals received dosages between 1.43 and 4.42 mg/kg body weight of nitenpyram in each given treatment. The criteria used to determine the drug efficacy were larval expulsion and fall. These were quantified at 15 min intervals within the first hour followed by 2, 3, 4, 6, and 18 h post-treatment. The highest larval expulsion happened between 1 and 2 h post-treatment. The spontaneous larval expulsion percentages were 86% and 94.11% for 6 and 18 h after the first treatment, respectively. Larvae were expelled until 18 h post-treatment. After this period the remaining dead larvae were mechanically removed. Nitenpyram showed 100% efficacy on the treatment of myiasis by C. hominivorax in naturally infested dogs.
Thaís R Correia; Fabio B Scott; Guilherme G Verocai; Clarissa P Souza; Julio I Fernandes; Raquel M P S Melo; Vanessa P C Vieira; Francisco A Ribeiro
Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2010-06-25
Journal Detail:
Title:  Veterinary parasitology     Volume:  173     ISSN:  1873-2550     ISO Abbreviation:  Vet. Parasitol.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-06     Completed Date:  2011-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7602745     Medline TA:  Vet Parasitol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  169-72     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier B.V. All rights reserved.
Departamento de Parasitologia Animal, Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, BR 465, Km 7 PSA/UFRRJ, Seropédica, RJ, Brazil.
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MeSH Terms
Diptera / drug effects,  physiology*
Dog Diseases / drug therapy,  parasitology*
Insecticides / administration & dosage,  therapeutic use*
Myiasis / drug therapy,  parasitology,  veterinary*
Pyridines / administration & dosage,  therapeutic use*
Reg. No./Substance:
0/Insecticides; 0/Pyridines; 0/nitenpyram

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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