Document Detail

Larvicidal constituents of Melantheria albinervia.
MedLine Citation:
PMID:  8824954     Owner:  NLM     Status:  MEDLINE    
Bioactivity-guided fractionation has led to the isolation of two larvicidal diterpenes, active against the yellow fever-transmitting mosquito Aedes aegypti, from a dichloromethane root extract of Melantheria albinervia (Asteraceae), a plant from Zimbabwe. These diterpenes were identified as ent-kaur-16-en-19-oic acid and 9(11),16-kauradien-19-oic acid. The diterpenes were also weakly active against Bacillus subtilis.
R Slimestad; A Marston; S Mavi; K Hostettmann
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Planta medica     Volume:  61     ISSN:  0032-0943     ISO Abbreviation:  Planta Med.     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-12-02     Completed Date:  1996-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0066751     Medline TA:  Planta Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  562-3     Citation Subset:  IM    
Institut de Pharmacognosie et Phytochimie, Université de Lausanne, Switzerland.
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MeSH Terms
Aedes / drug effects*,  embryology,  virology
Diterpenes / pharmacology*
Larva / drug effects*
Mosquito Control
Plants / chemistry*
Reg. No./Substance:
0/9(11),16-kauradien-19-oic acid; 0/Diterpenes; 20316-84-1/argyrophilic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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