Document Detail

Larvicidal activity of essential oil and methanol extract of Nepeta menthoides against malaria vector Anopheles stephensi.
MedLine Citation:
PMID:  23199714     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: To investigate the larvicidal activity of essential oil and methanol extract of the Nepeta menthoides (N. menthoides) against main malaria vector, Anopheles stephensi (An. stephensi).
METHODS: The essential oil of plant was obtained by Clevenger type apparatus and the methanol extract was supplied with Percolation method. Larvicidal activity was tested by WHO method. Twenty five fourth-instar larvae of An. stephensi were used in the larvicidal assay and four replicates were tested for each concentration. Five different concentrations of the oil and extract were tested for calculation of LC(50) and LC(90) values.
RESULTS: The LC(50) and LC(90) values were determined by probit analysis. LC(50) was 69.5 and 234.3 ppm and LC(90) was 175.5 and 419.9 ppm for the extract and essential oil respectively.
CONCLUSIONS: According to the results of this study methanolic extract of plant exhibited more larvicidal activity than essential oil. This could be useful for investigation of new natural larvicidal compounds.
Khanavi Mahnaz; Fallah Alireza; Vatandoost Hassan; Sedaghat Mahdi; Abai Mohammad Reza; Hadjiakhoondi Abbas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Asian Pacific journal of tropical medicine     Volume:  5     ISSN:  1995-7645     ISO Abbreviation:  Asian Pac J Trop Med     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101533720     Medline TA:  Asian Pac J Trop Med     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  962-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Hainan Medical College. Published by Elsevier B.V. All rights reserved.
Departments of Pharmacognosy, Faculty of Pharmacy and Traditional Iranian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran.
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