| Large volume leukapheresis: Efficacy and safety of processing patient's total blood volume six times. | |
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MedLine Citation:
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PMID: 21320801 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Large-volume leukapheresis (LVL) differs from standard leukapheresis by increased blood flow and an altered anticoagulation regimen. An open issue is to what degree a further increase in processed blood volume is reasonable in terms of higher yields and safety. In 30 LVL performed in patients with hematologic malignancies, 6 total blood volumes were processed. LVL resulted in a higher CD34+ cell yield without a change in graft quality. Although a marked platelet decrease can be expected, LVL is safe and can be recommended as the standard procedure for patients who mobilize low numbers of CD34+ cells and when high number of CD34+ cells are required. |
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Authors:
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Ines Bojanic; Klara Dubravcic; Drago Batinic; Branka Golubic Cepulic; Sanja Mazic; Darko Hren; Damir Nemet; Boris Labar |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-12 |
Journal Detail:
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Title: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis Volume: - ISSN: 1473-0502 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101095653 Medline TA: Transfus Apher Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Transfusion Medicine and Cellular Therapy, University Hospital Centre Zagreb, Kispaticeva 12, Croatia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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