| Large mucinous cystic neoplasm of the pancreas associated with pregnancy. | |
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MedLine Citation:
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PMID: 19084943 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mucinous cystic neoplasms (MCNs) of the pancreas occur mostly in females and are potentially sex hormone-sensitive. However, a MCN occurring during pregnancy is quite rare. A 30-year-old woman in the tenth week of pregnancy was referred to us because of a rapid increase in left hypochondrial distending pain. On ultrasound, the patient had a large intra-abdominal cystic lesion. She was thereafter diagnosed with missed abortion and a computed tomography scan showed that the lesion was a cystic tumor 18 cm in diameter originating from the pancreatic tail. The patient subsequently underwent tumor resection with distal pancreatectomy, sparing the spleen. Histopathological analysis of the specimen revealed a pancreatic MCN with moderate dysplasia. Immunohistochemically, the tumor was positive for both estrogen and progesterone receptors. To our knowledge, this is the first reported case of pancreatic MCN with moderate dysplasia in association with pregnancy. Our case strongly indicates that pancreatic MCN is female-hormone dependent. |
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Authors:
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Shin-ichi Ikuta; Tsukasa Aihara; Chiaki Yasui; Hiroya Iida; Hidenori Yanagi; Masao Mitsunobu; Ayako Kakuno; Naoki Yamanaka |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 14 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-12-16 Completed Date: 2009-05-19 Revised Date: 2010-09-22 |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 7252-5 Citation Subset: IM |
Affiliation:
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Department of Surgery, Meiwa General Hospital, Agenaruo 4-31, Nishinomiya, Hyogo 663-8186, Japan. ikuta@meiwa-hospital.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma, Mucinous
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diagnosis*,
metabolism,
surgery Adult Female Humans Pancreatic Neoplasms / diagnosis*, metabolism, surgery Pregnancy Pregnancy Complications, Neoplastic / diagnosis*, metabolism, surgery Receptors, Estrogen / metabolism Receptors, Progesterone / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Estrogen; 0/Receptors, Progesterone |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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