Document Detail

Large extracoronary artery diameter in obese postmenopausal women.
MedLine Citation:
PMID:  20395875     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim of this study was to investigate the association between extracoronary artery diameter (brachial and carotid arteries) and obesity. METHODS: This was a cross-sectional study conducted among women referred to the Menopause Clinic of the University of Catanzaro. The study included 102 obese and 102 nonobese (controls) postmenopausal women. Medical histories were reviewed, and participants underwent clinical and biochemical evaluations to assess risk factors for cardiovascular disease. Common carotid artery and brachial artery diameters and atherosclerotic lesions were evaluated by ultrasonography. Associations between brachial artery and common carotid artery diameters with age, body mass index, waist circumference, and cardiovascular risk factors were analyzed by stepwise multivariate analysis. RESULTS: Brachial and common carotid artery diameters were significantly greater in obese women than in nonobese women. After adjustment for confounding variables, brachial artery diameter but not common carotid artery diameter correlated with obesity (beta = 0.229, P = 0.002) and with waist circumference (beta = 0.013, P < 0.001) independently of systolic blood pressure and other risk factors. CONCLUSIONS: Extracoronary artery diameter measurement, if confirmed by other studies, may be considered a useful tool to assess vascular remodeling in obese postmenopausal women.
Tiziana Montalcini; Antonietta Fava; Alberto Castagna; Gaetano Gorgone; Carmine Gazzaruso; Arturo Pujia
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Menopause (New York, N.Y.)     Volume:  17     ISSN:  1530-0374     ISO Abbreviation:  Menopause     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-05-10     Completed Date:  2010-08-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433353     Medline TA:  Menopause     Country:  United States    
Other Details:
Languages:  eng     Pagination:  611-4     Citation Subset:  IM    
Department of Clinical and Experimental Medicine, University of Catanzaro, 88100 Catanzaro, Italy.
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MeSH Terms
Body Mass Index
Brachial Artery / pathology*,  ultrasonography*
Carotid Artery Diseases / etiology,  ultrasonography
Carotid Artery, Common / pathology*,  ultrasonography*
Cross-Sectional Studies
Middle Aged
Multivariate Analysis
Obesity / complications*,  pathology,  ultrasonography*
Organ Size
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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