Document Detail


Large demyelinating brain lesion mimicking a herniating tumor.
MedLine Citation:
PMID:  11808857     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe the case of a large brain lesion whose computed tomography appearance and clinical evolution mimicked a herniating tumor. The patient progressed to coma within 6 days of hospitalization despite high-dose steroid treatment. Emergency excision of the lesion was carried out. Histological analysis showed massive demyelination, axon preservation and no tumor cells. No lesion recurrence was seen during a 55-month follow-up. Recognition of such lesions through magnetic resonance imaging or spectroscopy may spare unnecessary surgery or biopsy. However, our case shows that such lesions may still require resection in the face of a rapid clinical progression and poor response to medical treatment.
Authors:
B Censori; C Agostinis; T Partziguian; G Gazzaniga; F Biroli; A Mamoli
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology     Volume:  22     ISSN:  1590-1874     ISO Abbreviation:  Neurol. Sci.     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2002-01-25     Completed Date:  2002-07-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100959175     Medline TA:  Neurol Sci     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  325-9     Citation Subset:  IM    
Affiliation:
UO Neurology 2, Ospedali Riuniti, Bergamo, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain Neoplasms / pathology*,  surgery
Diagnosis, Differential
Diffuse Cerebral Sclerosis of Schilder / pathology*,  surgery
Humans
Magnetic Resonance Imaging
Male
Multiple Sclerosis / pathology*,  surgery
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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