Document Detail

Large-cell neuroendocrine carcinoma in the thymus.
MedLine Citation:
PMID:  19002759     Owner:  NLM     Status:  MEDLINE    
Large-cell neuroendocrine carcinoma in the thymus is a rare cancer that is more aggressive and leads to a poorer prognosis than other thymic epithelial tumors. A 67-year-old woman presented with an anterior mediastinal mass in the thymus. Histological examination after thymectomy revealed large-cell neuroendocrine carcinoma in the thymus. Although the patient received postoperative chemotherapy and radiotherapy, a distant relapse was detected 6 months after the surgery. We reviewed nine cases of this rare cancer that have been reported in Japan. There is no evidence of to support postoperative therapy for large-cell neuroendocrine carcinoma in the thymus. However, it is essential to accumulate and study these cases to understand this disease and prolong patient survival.
Seiji Mega; Mitsuru Oguri; Ryosuke Kawasaki; Kazuaki Hazama; Kazuhiro Iwai; Satoshi Kondo
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-11-12
Journal Detail:
Title:  General thoracic and cardiovascular surgery     Volume:  56     ISSN:  1863-6705     ISO Abbreviation:  -     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-11-12     Completed Date:  2009-01-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101303952     Medline TA:  Gen Thorac Cardiovasc Surg     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  566-9     Citation Subset:  IM    
Division of Surgery, Oji General Hospital, 3-4-8 Wakakusachyo, Tomakomai, Hokkaido 053-8506, Japan.
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MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Carcinoma, Neuroendocrine* / diagnosis,  drug therapy,  pathology,  radiography,  radiotherapy,  surgery
Combined Modality Therapy
Fatal Outcome
Follow-Up Studies
Magnetic Resonance Imaging
Neoplasm Recurrence, Local
Neoplasm Staging
Radiotherapy Dosage
Thymus Gland / pathology
Thymus Neoplasms* / diagnosis,  drug therapy,  pathology,  radiography,  radiotherapy,  surgery
Time Factors
Tomography, X-Ray Computed

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