| Large artery involvement in giant cell (temporal) arteritis. | |
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MedLine Citation:
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PMID: 1200525 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Of 248 patients with giant cell arteritis, 34 had evidence that the disease affected the aorta or its major branches. Symptoms suggestive of large artery involvement were intermittent claudication of an extremity, paresthesias, and Raynaud's phenomenon. Physical findings included absent or decreased large artery pulses and bruits over large arteries. Four patients presented with decreased upper extremity pulses as the initial manifestation of their arteritis. Nine other patients under treatment for temporal arteritis or polymyalgia rheumatica first developed evidence of large artery involvement as corticosteroid therapy was tapered or discontinued. Angiography, performed in 10 patients, was helpful in indicating arteritis rather than atherosclerosis as the cause of large artery disease. Three patients died with aortic rupture, and, at autopsy, widespread giant cell arteritis was found. However, when corticosteroids were given in adequate doses, the response was favorable in most patients; intermittent claudication decreased and the pulses improved. |
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Authors:
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R G Klein; G G Hunder; A W Stanson; S G Sheps |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Annals of internal medicine Volume: 83 ISSN: 0003-4819 ISO Abbreviation: Ann. Intern. Med. Publication Date: 1975 Dec |
Date Detail:
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Created Date: 1976-02-13 Completed Date: 1976-02-13 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372351 Medline TA: Ann Intern Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 806-12 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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administration & dosage,
therapeutic use Aged Aortic Diseases* / complications, radiography Aortography Arteritis / complications* Blood Sedimentation Female Giant Cell Arteritis / complications*, diagnosis, drug therapy, pathology, radiography Humans Intermittent Claudication / complications Male Middle Aged Renal Artery Urine / cytology |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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