| Large-scale investigation into dumping syndrome after gastrectomy for gastric cancer. | |
| | |
MedLine Citation:
|
PMID: 20829078 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The aim of this study was to investigate early and late dumping syndromes in a large number of patients after gastrectomy for gastric cancer. STUDY DESIGN: Responses to questions on a visual analogue scale survey completed by 1,153 gastrectomy patients were analyzed for associations between clinical factors and occurrence of dumping syndrome. Types of gastrectomy included distal gastrectomy with Billroth I or with Roux-Y reconstruction, pylorus preserving gastrectomy, proximal gastrectomy, and total gastrectomy. RESULTS: Based on the visual analogue scale rating of symptomatic discomfort, patients were categorized into 1 of 2 groups: symptom-free or symptomatic. Incidences of early or late dumping syndrome in all patients were 67.6% and 38.4%, respectively. Patients in whom early dumping syndrome developed were significantly more likely to experience late dumping syndrome than those in whom it did not develop (p < 0.001). According to multivariate analyses, factors that decreased the risk for developing early dumping syndrome were reduced weight loss (p < 0.01), old age (p < 0.01), pylorus preserving gastrectomy (p < 0.01), distal gastrectomy with Roux-Y reconstruction (p < 0.01), and distal gastrectomy with Billroth I (p = 0.019). In addition, factors that decreased the risk of developing late dumping syndrome were reduced weight loss (p = 0.03), being male (p < 0.01), pylorus preserving gastrectomy (p < 0.01), and distal gastrectomy with Roux-Y reconstruction (p < 0.01). No other clinical factors (lymph node dissection, vagal nerve preservation, and postoperative period) showed a substantial association with the occurrence of dumping syndrome in multivariate analyses. CONCLUSIONS: Substantially more patients suffered from early dumping syndrome than late dumping syndrome after gastrectomy. Two clinical factors, surgical procedures and amount of body weight loss, associated significantly with the occurrence of both early and late dumping syndrome. |
| | |
Authors:
|
Shinji Mine; Takeshi Sano; Kenji Tsutsumi; Yoshitaka Murakami; Kazuhisa Ehara; Makoto Saka; Kazuo Hara; Takeo Fukagawa; Harushi Udagawa; Hitoshi Katai |
Related Documents
:
|
10610048 - Timing of puberty and syndromes of schizotypy: a replication. 20306898 - Catastrophic rapid onset heparin-induced thrombocytopenia--victim of our own success. 17670008 - Repair of adult scimitar syndrome with an intra-atrial conduit. 1012458 - Neocortical reactivity to peripheral stimuli in neurotics. 20430198 - The risk factors for cytomegalovirus syndrome and tissue-invasive cytomegalovirus disea... 12553498 - The use of corticosteroids in severe sepsis and acute respiratory distress syndrome. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-09-15 |
Journal Detail:
|
Title: Journal of the American College of Surgeons Volume: 211 ISSN: 1879-1190 ISO Abbreviation: J. Am. Coll. Surg. Publication Date: 2010 Nov |
Date Detail:
|
Created Date: 2010-11-01 Completed Date: 2010-12-08 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9431305 Medline TA: J Am Coll Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 628-36 Citation Subset: AIM; IM |
Copyright Information:
|
Copyright © 2010 American College of Surgeons. Published by Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Gastroenterological Surgery, Toranomon Hospital, Tokyo, Japan. shinji.mine@jfcr.or.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Causality Disease-Free Survival Dumping Syndrome / diagnosis, epidemiology*, etiology Female Follow-Up Studies Gastrectomy / adverse effects, statistics & numerical data* Humans Incidence Logistic Models Male Middle Aged Pain Measurement Population Surveillance Questionnaires Reproducibility of Results Stomach Neoplasms / surgery* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Prevention of parastomal herniation with biologic/composite prosthetic mesh: a systematic review and...
Next Document: The relationship between case volume, care quality, and outcomes of complex cancer surgery.