Document Detail

Large multifocal cardiac myxoma causing the sudden unexpected death of a 2-month-old infant--a rapidly growing, acquired lesion versus a congenital process?: a case report.
MedLine Citation:
PMID:  21512386     Owner:  NLM     Status:  MEDLINE    
We report the occurrence of a clinically undiagnosed biatrial myxoma with left ventricular involvement in a 2-month-old male infant, resulting in sudden death. During a routine well-baby examination, a grade (34) holosystolic murmur was detected at the left sternal border with radiation to the axilla and back. On the following day, the patient collapsed and died suddenly. An autopsy revealed a large multifocal neoplasm diffusely involving the aortic valve while displaying mitral, tricuspid, and left ventricular extensions. The ensuing histopathologic and immunohistochemical studies were diagnostic for myxoma. We discuss the occurrence of cardiac myxoma within the pediatric population and review the literature as to theorize whether this lesion was a congenital process versus a rapidly growing tumor that developed after the child was born. Lastly, we address the potential for sudden death in patients with such tumors.
Kiyoe Kure; Daniel Lingamfelter; Eugenio Taboada
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of forensic medicine and pathology     Volume:  32     ISSN:  1533-404X     ISO Abbreviation:  Am J Forensic Med Pathol     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-13     Completed Date:  2011-09-27     Revised Date:  2013-03-25    
Medline Journal Info:
Nlm Unique ID:  8108948     Medline TA:  Am J Forensic Med Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  166-8     Citation Subset:  IM    
University of Missouri-Kansas City and Truman Medical Centers, Kansas City, MO, USA.
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MeSH Terms
Cardiomegaly / etiology,  pathology
Death, Sudden / etiology*
Forensic Pathology
Heart Murmurs / diagnosis
Heart Neoplasms / congenital,  pathology*
Heart Valves / pathology
Heart Ventricles / pathology
Myocardium / pathology
Myxoma / congenital,  pathology*
Comment In:
Am J Forensic Med Pathol. 2013 Mar;34(1):e2   [PMID:  23403481 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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