Document Detail


Large adrenal oncocytoma with uncertain malignant potential: case report and review of literature.
MedLine Citation:
PMID:  20061289     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To report a case of oncocytoma, a relatively rare adrenal tumor, which most commonly is detected as an adrenal incidentaloma.
METHODS: We present a case report, including laboratory, imaging, and pathologic findings, of a 47-year-old obese woman who had hypertension and an incidentally found large, left adrenal mass.
RESULTS: On the basis of the hormonal evaluation, this mass was a nonsecreting adrenal tumor, which histologically proved to be an oncocytoma with borderline malignant characteristics. A collective analysis of the few cases of adrenal oncocytoma published in the medical literature showed that our case corresponded to the previously published cases in preponderant location (left side) as well as the general size (11.4 cm in the largest dimension) and weight (372 g).
CONCLUSION: Adrenal oncocytoma should be included in the differential diagnosis of adrenal incidentalomas, especially if large tumors are detected. In addition, a longterm follow-up is suggested because there are no certain clues about the true potential of this tumor.
Authors:
Melpomeni Peppa; Evi Karamitopoulou; Panagiotis Nikolopoulos; Georgios Peros; Theofanis Economopoulos; Sotirios A Raptis; Dimitrios Hadjidakis
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists     Volume:  16     ISSN:  1934-2403     ISO Abbreviation:  Endocr Pract     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-08-13     Completed Date:  2010-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9607439     Medline TA:  Endocr Pract     Country:  United States    
Other Details:
Languages:  eng     Pagination:  641-5     Citation Subset:  IM    
Affiliation:
Endocrine Unit, Second Department of Internal Medicine-Propaedeutic, Research Institute and Diabetes Center, Athens University Medical School, Attikon University Hospital, Athens, Greece. molypepa@otenet.gr
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MeSH Terms
Descriptor/Qualifier:
Adenoma, Oxyphilic / complications,  diagnosis*,  pathology
Adrenal Gland Neoplasms / complications,  diagnosis*,  pathology
Adrenocortical Adenoma / complications,  diagnosis,  pathology
Diagnosis, Differential
Female
Humans
Hypertension / complications
Incidental Findings
Magnetic Resonance Imaging
Middle Aged
Obesity / complications
Precancerous Conditions / complications,  diagnosis*,  pathology
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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