| A Laplace pressure based microfluidic trap for passive droplet trapping and controlled release. | |
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MedLine Citation:
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PMID: 22662095 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Here, we present a microfluidic droplet trap that takes advantage of the net Laplace pressure force generated when a droplet is differentially constricted. Mathematical simulations were first used to understand the working range of the component; followed by finite element modeling using the CFD software package to further characterize the behavior of the system. Controlled release of the trapped droplets is also demonstrated through both a mechanical method and a chemical method that manipulates the total pressure exerted on the trapped droplet. The unique design of this trapping device also provides the capability for selection of a single droplet from a train, as well as droplet fusion. |
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Authors:
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Melinda G Simon; Robert Lin; Jeffrey S Fisher; Abraham P Lee |
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Publication Detail:
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Type: Journal Article Date: 2012-02-24 |
Journal Detail:
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Title: Biomicrofluidics Volume: 6 ISSN: 1932-1058 ISO Abbreviation: Biomicrofluidics Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-06-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101293825 Medline TA: Biomicrofluidics Country: United States |
Other Details:
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Languages: eng Pagination: 14110-1411013 Citation Subset: - |
Affiliation:
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Department of Biomedical Engineering, University of California, Irvine, 3201 Natural Sciences II, Irvine, California 92697, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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