Document Detail


A Laplace pressure based microfluidic trap for passive droplet trapping and controlled release.
MedLine Citation:
PMID:  22662095     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Here, we present a microfluidic droplet trap that takes advantage of the net Laplace pressure force generated when a droplet is differentially constricted. Mathematical simulations were first used to understand the working range of the component; followed by finite element modeling using the CFD software package to further characterize the behavior of the system. Controlled release of the trapped droplets is also demonstrated through both a mechanical method and a chemical method that manipulates the total pressure exerted on the trapped droplet. The unique design of this trapping device also provides the capability for selection of a single droplet from a train, as well as droplet fusion.
Authors:
Melinda G Simon; Robert Lin; Jeffrey S Fisher; Abraham P Lee
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Publication Detail:
Type:  Journal Article     Date:  2012-02-24
Journal Detail:
Title:  Biomicrofluidics     Volume:  6     ISSN:  1932-1058     ISO Abbreviation:  Biomicrofluidics     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-06-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101293825     Medline TA:  Biomicrofluidics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  14110-1411013     Citation Subset:  -    
Affiliation:
Department of Biomedical Engineering, University of California, Irvine, 3201 Natural Sciences II, Irvine, California 92697, USA.
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