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Laparoscopic marsupialization of a giant posttraumatic splenic cyst.
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MedLine Citation:
PMID:  15554287     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND OBJECTIVE: Nonparasitic cysts are rare clinical lesions of the spleen. Causes include congenital malformations and trauma. Historically, management has entailed partial or total splenectomy using an open approach. Recently, laparoscopic approaches have been developed. In this report, we describe laparoscopic marsupialization of a giant splenic cyst (diameter > 15 cm).
METHODS: A 25-year-old African-American man presented with a 9-month history of early satiety, constipation, and left upper quadrant pain. Additionally, he reported blunt trauma to the abdomen 2 years earlier. Physical examination revealed a large, fixed, nontender left upper quadrant mass. Computed tomography scan confirmed a simple cyst within the spleen, measuring 20 x 25 cm. Echinococcus and Entamoeba histolytica serologies were negative. Laparoscopic exploration was performed. Four liters of brown fluid were aspirated and intraoperative cytology confirmed a nonparasitic cyst. The cyst wall was excised and the cavity was packed with omentum.
RESULTS: The patient's recovery was uneventful, and he was discharged to home tolerating a regular diet on postoperative day 3. At 6-month follow-up, the patient was asymptomatic and showed no evidence of recurrence.
CONCLUSION: Nonparasitic splenic cysts are rare lesions. Laparoscopic marsupialization is safe and effective for giant nonparasitic splenic cysts and should be considered the treatment of choice.
Authors:
Rafael Sierra; William C Brunner; Joseph T Murphy; J Bruce Dunne; Daniel J Scott
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons     Volume:  8     ISSN:  1086-8089     ISO Abbreviation:  JSLS     Publication Date:    2004 Oct-Dec
Date Detail:
Created Date:  2004-11-19     Completed Date:  2005-03-03     Revised Date:  2013-03-26    
Medline Journal Info:
Nlm Unique ID:  100884618     Medline TA:  JSLS     Country:  United States    
Other Details:
Languages:  eng     Pagination:  384-8     Citation Subset:  IM    
Affiliation:
Tulane Center for Minimally Invasive Surgery, Tulane University Health Sciences Center, New Orleans, Louisiana, USA.
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MeSH Terms
Descriptor/Qualifier:
Abdominal Injuries / complications
Adult
Cysts / surgery*
Humans
Laparoscopy / methods*
Male
Spleen / injuries,  surgery*
Splenic Diseases / etiology,  surgery*
Treatment Outcome
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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Journal ID (nlm-ta): JSLS
Journal ID (hwp): jsls
Journal ID (pmc): jsls
Journal ID (publisher-id): JSLS
ISSN: 1086-8089
ISSN: 1938-3797
Publisher: Society of Laparoendoscopic Surgeons, Miami, FL
Article Information
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© 2004 by JSLS, Journal of the Society of Laparoendoscopic Surgeons.
open-access:
Print publication date: Season: Oct–Dec Year: 2004
Volume: 8 Issue: 4
First Page: 384 Last Page: 388
ID: 3016817
PubMed Id: 15554287

Laparoscopic Marsupialization of a Giant Posttraumatic Splenic Cyst
Rafael Sierra, MD Affiliation: Tulane Center for Minimally Invasive Surgery, Tulane University Health Sciences Center, New Orleans, Louisiana, USA.
William C. Brunner, MD Affiliation: Tulane Center for Minimally Invasive Surgery, Tulane University Health Sciences Center, New Orleans, Louisiana, USA.
Joseph T. Murphy, MD Affiliation: University of Texas Southwestern Medical Center, Dallas, Texas, USA.
J. Bruce Dunne, PhD Affiliation: Tulane Center for Minimally Invasive Surgery, Tulane University Health Sciences Center, New Orleans, Louisiana, USA.
Daniel J. Scott, MD Affiliation: Tulane Center for Minimally Invasive Surgery, Tulane University Health Sciences Center, New Orleans, Louisiana, USA.
Correspondence: Address reprint requests to: Daniel J. Scott, MD, Department of Surgery, SL-22, 1430 Tulane Ave, New Orleans, LA 70112-2699, USA. Telephone: 504 588 5136, Fax: 504 988 6638, E-mail: dscott@tulane.edu

INTRODUCTION

Splenic cysts are rare lesions and should be suspected when a mass is noted in the left upper quadrant. The traditional classification divides them into “true” cysts (primary) and pseudocysts (secondary) on the basis of the presence or absence of an epithelial lining. Primary cysts can be subdivided into those with parasitic and those with nonparasitic causes. Secondary cysts are usually seen following abdominal trauma and are thought to be a late complication of an intrasplenic hematoma. Such cysts may become quite large, and cysts greater than 15 cm in size are considered giant.1

Formerly, the treatment of choice for secondary cysts consisted of total splenectomy via an open approach.2,3 However, due to the small, but real, risk of overwhelming postsplenectomy sepsis (OPSI), spleen-sparing techniques have been developed.4 Additionally, advances in minimally invasive surgery have resulted in effective treatment with less morbidity. Although laparoscopic hemisplenectomy has been reported, most nonparasitic splenic cysts (NPSC) may be unroofed, or marsupialized, with good results.3,5 In this paper, we present a case in which a giant splenic cyst was successfully treated by laparoscopic marsupialization.


CASE REPORT

A 25-year-old African-American male presented with a 9-month history of early satiety, constipation, and left upper quadrant abdominal pain. The patient reported that 1 year prior to presentation he was involved in a motor vehicle collision without apparent injury. He also reported blunt trauma to the abdomen during an altercation 2 years earlier.

Physical examination revealed a large firm, fixed, non-tender, left upper quadrant mass (Figures 1 and 2); the rest of the physical examination was unremarkable. A computed tomography (CT) scan of the abdomen confirmed a single splenic cyst measuring 20 x 25 cm, exerting a significant mass effect on the surrounding organs (Figure 3). As seen on the CT scan, the stomach, duodenum, and pancreas were displaced medially, and the left kidney was compressed posteriorly. Serologies for Echinococcus and Entamoeba histolytica were negative. Because of the symptoms and size of the cyst, surgery was recommended, and the patient agreed to proceed. Preoperatively, pneumococcal, haemofilus influenzae, and meningococcal vaccines were administrated.

After induction of general anesthesia, the patient was placed in the supine position. After establishing pneumoperitoneum, a 30° laparoscope was inserted through an umbilical port. The abdomen was explored, and a giant splenic cyst was identified (Figure 4). The mass displaced the transverse colon inferiorly, and large varices were noted in the gastrocolic ligament due to venous compression. Two additional 10-mm trocars were placed in the left and right lower abdominal quadrants. A sample of fluid was aspirated from the cyst to confirm the diagnosis. The fluid was dark brown in color, and cytologic examination showed no ova, cysts or parasites, no malignant cells, and abundant hemosiderin-laden macrophages, consistent with trauma. Four liters of fluid were removed before the cyst was completely decompressed. The cyst was then widely unroofed by excising the entire anterior wall using the Harmonic scalpel (Ethicon Endo-Surgery, Cincinnati, OH). Two additional 5-mm ports were placed in the upper abdomen to facilitate cyst wall excision near the diaphragm. The wall thickness varied from several millimeters to well over a centimeter in some places. Bleeding was generally controlled with the Harmonic scalpel, but suture ligation of larger vessels using the Endostich device (United States Surgical Corporation, Norwalk, CT) was required in several places. After unroofing, the trabecular cyst lining was visualized and debris was removed (Figure 5); thus, complete marsupialization was achieved. Although the omentum had been stretched thin by the mass effect from the cyst, sufficient omentum was available to pack the cavity and obliterate the dead space (Figure 6). Several sutures were used to hold the omentum in place. The cyst wall was placed in a specimen bag and retrieved through a 10-mm port site in a piecemeal fashion.

Gross pathologic examination showed a dark brown cyst lining and hemorrhagic debris (Figure 7). Microscopic evaluation confirmed a benign cyst wall with abundant hemorrhage and hemosiderin-laden macrophages. In most of the cyst wall, no epithelium could be identified; but in a small area, a mesothelial lining was found (Figure 8). The operation was completed in 3 hours, and the patient was discharged to home on the third postoperative day. At 6-month follow-up, the patient was free of symptoms and showed no signs of recurrence.


DISCUSSION

In 1790, Berthelot described the first echinococcal splenic cyst, and in 1829, Andral described the first NPSC.6 Since then, approximately 800 cases of NPSC have been reported, and a recent increase has occurred in the incidence of posttraumatic cysts.7

Several classifications for splenic cysts exist. The most widely adopted is that of McClure and Altemeier,8 which is a modification from the first classification published by Fowler in 1912,9 and divides splenic cysts into 2 groups. A specific secreting membrane lines primary or true cysts. The lining may be epithelial, endothelial, or parasitic. Echinococcus is the most common parasitic cause, and most other primary cysts are congenital. False or secondary cysts do not have a secreting lining and may be serous, inflammatory, degenerative, or hemorrhagic. Blunt abdominal trauma with occult injury of the spleen is the most common cause for secondary cysts.

Morgenstern1 has recently questioned the validity of the traditional classification criteria for NPSC. On microscopic examination, Morgenstern was able to identify an epithelial lining and concluded that most NPSCs are congenital in nature, regardless of a history of trauma. Therefore, Morgenstern recommended that according to cause alone, cysts should be classified as congenital, neoplastic, traumatic, or degenerative. Although our patient clearly had a posttraumatic cyst, a mesothelial lining was identified in a portion of the cyst wall, which is consistent with Morgenstern's findings.

Abdominal trauma is responsible for approximately 75% of secondary splenic cysts.7 Although a history of trauma can be elicited in only 30% of the patients, a traumatic cause can be confirmed grossly by the presence of shaggy, hemorrhagic debris, and microscopically by hemosiderin-laden macrophages.1,10 Posttraumatic cysts are formed either by encapsulation of a hematoma or by infoliation of splenic capsule fragments.11 Posttraumatic splenic cysts are asymptomatic in 30% of patients and are frequently diagnosed incidentally during imaging studies obtained for other purposes.12 However, 70% of patients present with symptoms, the severity of which are related to the size of the cyst. Small cysts may simply cause abdominal pain, whereas large cysts may exert a mass effect and cause early satiety, nausea, vomiting, constipation, or hydronephrosis.2,3

Patients with a suspected splenic cyst may have a palpable mass on physical examination, but often do not. Other causes of splenomegaly, including myeloid metaplasia, hemolytic anemia, mononucleosis, and portal hypertension must be excluded.13 Ultrasound and CT imaging may help to distinguish cystic from solid lesions and to characterize cyst loculations.2 Posttraumatic cysts are usually unilocular, whereas parasitic cysts are usually multilocular.3 Serologic studies are useful to exclude a parasitic cause.

Although the natural history of secondary splenic cysts is not completely known, a risk exists of rupture, infection, or hemorrhage. Asymptomatic patients with small cysts (<5 cm) may be observed and usually do not require treatment. For symptomatic patients and for large cysts (>5 cm), surgical treatment is indicated. Historically, the treatment of choice for NPSCs has been total splenectomy. Although splenectomy may be indicated for patients with parasitic cysts, spleen-sparing techniques have evolved as the treatment of choice for NPSCs so that the risk of OPSI may be avoided. The incidence of OPSI is 3.3% to 4.4% among children and 0.9% to 3.2% in adults, with mortality ranging from 0.8% to 4.4%.14,15 The organisms most frequently associated with OPSI are Streptococcus pneumoniae, Neisseria meningitides, Escherichia coli, and Haemofilus influenzae, and vaccinations should be administrated.14,16

Spleen-sparing techniques, such as percutaneous drainage with or without injection of a sclerosing agent, have been described but result in a high rate of recurrence.17, , 19 On the other hand, partial splenectomy and marsupialization via an open approach have proven effective.20,21 Laparoscopic approaches for both techniques have recently proven feasible and result in less postoperative morbidity.3,22,23 For our patient, a partial splenectomy was unnecessary because the cyst was broad-based and amenable to unroofing. For deeply seated, narrow-based cysts, a hemisplenectomy may be indicated to prevent recurrence.


CONCLUSION

Nonparasitic splenic cysts are rare lesions but may be associated with significant symptoms. Laparoscopic marsupialization is safe and effective, and is feasible even for Laparoscopic Marsupialization of a Giant Posttraumatic Splenic Cyst, Sierra R et al. giant cysts, as described in this paper. In the current era, a laparoscopic spleen-sparing technique should be considered the treatment of choice.


References:
1.. Morgenstern L. Nonparasitic splenic cysts: pathogenesis, classification, and treatment. J Am Coll Surg. Year: 2002;194(3):306–31411893134
2.. Cinzia L,Konstantinos NH,Adil RET,Nadey SH. Posttraumatic cyst of the spleen: a case report and review of the literature. Int Surg. Year: 2002;87:152–15612403089
3.. Smith SF,Scott DJ,Burdick JS,Rege RV,Jones DB. Laparoscopic marsupialization and hemisplenectomy for splenic cysts. J Laparoendosc Adv Surg Tech A. Year: 2001;11(4):243–24911569516
4.. Rege RV,Merrian LT,Joehl RJ. Laparoscopic splenectomy. Surg Clin North Am. Year: 1996;76:459–4688669006
5.. Jamshidi M,Chang E,Smaroff G,Mehta J,Chani A. Laparoscopic fenestration and modified marsupialization of posttraumatic splenic cysts using a harmonic scalpel. Surg Endosc. Year: 2001; 15(7):75811591989
6.. Andral G. Précis d'anatomie pathologique. Paris, Year: 1829
7.. Pachter HL,Hofstetter SR,Elkowits A,Harris A,Liang HG. Traumatic cyst of the spleen–the role of cystectomy and splenic preservation: experience with seven consecutive patients. J Trauma. Year: 1993;35:430–4368371303
8.. McClure RD,Altemeier A. Cyst of the spleen. Ann Surg. Year: 1942;116:98–10217858077
9.. Fowler RH. Cysts of the spleen: a pathological and surgical study. Am Surg. Year: 1913;57:658–690
10.. Dachman AH,Ross PR,Murari PJ,Olmsted WW,Lichtenstein JE. Non parasitic splenic cysts: a report of 52 cases with radiologic-pathologic correlations. Am J Roentgenol. Year: 1986;147:537–5423526842
11.. Monasch S. Cysts of the spleen. Trop Geogr Med. Year: 1970;22:486–4935497384
12.. Qureshi MA,Hafner CD. Clinical manifestations of splenic cysts: study of 75 cases. Am Surg. Year: 1965;31:605–60814326973
13.. Knudson P,Coon W,Schnitzer B,Liepman M,Arbor A. Splenomegaly without an apparent cause. Surg Gynecol Obstet. Year: 1982;155:705–7087135177
14.. Bisharat N,Omari H,Lavi I,Raz R. Risk of infection and death among post splenectomy patients. J Infect. Year: 2001;43:182–18611798256
15.. Holdsworth R,Irving A,Cashieri A. Postsplenectomy sepsis and its mortality rate: actual versus perceived risks. Br J Surg. Year: 1991;78:1031–10381933181
16.. Singer DB. Postsplenectomy sepsis. Perspect Pediatr Pathol. Year: 1973;1:285–3114596312
17.. Carpenter G,Cotter PW,Davidson JR. Epidermoid cyst of the spleen. Aust N Z J Surg. Year: 1986;56:365–3683521571
18.. Moir C,Guttman F,Jequier S,Sonnino R,Youssef S. Splenic cysts: aspiration, sclerosis, or resection. J Pediatr Surg. Year: 1989;27:646–6482754580
19.. Goldfinger M,Cohen MM,Steinhardt MI,Rothberg R,Rother I. Sonography and percutaneous aspiration of splenic epidermoid cyst. J Clin Ultrasound. Year: 1986;14:147–1493081590
20.. Ehrlich P,Jamieson CG. Nonparasitic splenic cysts: a case report and review. Can J Surg. Year: 1990;33:306–3082200598
21.. Williams RJ,Glazer G. Splenic cysts: changes in diagnosis, treatment and aetiological concepts. Ann R Coll Surg Engl. Year: 1993; 75:87–898476192
22.. Van der Zee DC,Kramer WL,Ure BM,Mokhaberi B,Bax NMA. Laparoscopic management of a large posttraumatic splenic cyst in a child. Surg Endosc. Year: 1999;13:1241–124210594276
23.. Ho CM. Splenic cysts: a new approach to partial splenectomy. Surg Endosc. Year: 2002;16:71711972232

Figures

[Figure ID: F1]
Figure 1. 

Anterior view of patient's abdomen before surgery, showing an obvious mass in the left upper quadrant.



[Figure ID: F2]
Figure 2. 

Lateral view of patient's abdomen before surgery, showing a large protrusion anteriorly in the abdominal wall.



[Figure ID: F3]
Figure 3. 

Computed tomography scan of the abdomen showing the cyst and its mass effect on the surrounding structures. A small rim of splenic tissue can be seen at the posterior aspect of the cyst.



[Figure ID: F4]
Figure 4. 

Laparoscopic view of the giant splenic cyst with a thin covering of omentum. An aspiration needle was inserted for decompression.



[Figure ID: F5]
Figure 5. 

Laparoscopic view of the cystic cavity and debris.



[Figure ID: F6]
Figure 6. 

Laparoscopic view of the unroofed cyst with omental packing.



[Figure ID: F7]
Figure 7. 

Fragments of the cyst wall after specimen retrieval.



[Figure ID: F8]
Figure 8. 

Microscopic view of the cyst wall with identification of a segment of mesothelial lining (inset).



Article Categories:
  • Case Reports

Keywords: Nonparasitic splenic cyst, Laparoscopic marsupialization, Laparoscopic surgery, Spleen.

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