Document Detail

Laparoscopic adrenalectomy: 100 resections with clinical long-term follow-up.
MedLine Citation:
PMID:  15624053     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The operative results of 100 laparoscopic adrenal resections in 94 patients and the subsequent impact on postoperative antihypertensive therapy are presented. METHODS: Clinical and follow-up data for resections performed between 1995 and 2003 were obtained from medical records, patient questionnaires, and telephone interviews. RESULTS: The diseases included Conn's syndrome (27 patients), Cushing's syndrome (30 patients), pheochromocytoma (11 patients), and Other tumors (26 patients). Antihypertensive therapy was eliminated or reduced for Conn's syndrome (75%), Cushing's syndrome (27%), pheochromocytoma (88%) and patients with Other tumors (54%). Clinical improvement was observed by 12 months for pheochromocytoma patients as compared with 35 to 45 months for the other groups (p < 0.05). Multivariate analysis showed that pheochromocytoma patients were more likely to experience improvement or cure than the Other tumor group (hazard ratio, 4.87; 95% confidence interval, 1.61-14.7). CONCLUSIONS: Laparoscopic adrenalectomy continues to be safe and efficacious for benign adrenal diseases. Although patients with functional tumors can expect improvement or cure, the time until improvement may be longer than previously recognized.
B K Poulose; M D Holzman; O B Lao; E L Grogan; R E Goldstein
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Publication Detail:
Type:  Journal Article     Date:  2004-12-30
Journal Detail:
Title:  Surgical endoscopy     Volume:  19     ISSN:  1432-2218     ISO Abbreviation:  Surg Endosc     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-06-16     Completed Date:  2006-06-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8806653     Medline TA:  Surg Endosc     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  379-85     Citation Subset:  IM    
Vanderbilt University School of Medicine, D-5203 Medical Center North, 1161 21st Avenue, Nashville, TN 37232, USA.
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MeSH Terms
Adrenal Gland Diseases / complications,  surgery*
Adrenalectomy / adverse effects,  methods*,  statistics & numerical data*
Antihypertensive Agents / therapeutic use
Cohort Studies
Follow-Up Studies
Hypertension / drug therapy,  etiology
Middle Aged
Multivariate Analysis
Postoperative Complications / epidemiology,  etiology
Time Factors
Reg. No./Substance:
0/Antihypertensive Agents

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