Document Detail


Laparoscopic adrenalectomy: 100 resections with clinical long-term follow-up.
MedLine Citation:
PMID:  15624053     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The operative results of 100 laparoscopic adrenal resections in 94 patients and the subsequent impact on postoperative antihypertensive therapy are presented. METHODS: Clinical and follow-up data for resections performed between 1995 and 2003 were obtained from medical records, patient questionnaires, and telephone interviews. RESULTS: The diseases included Conn's syndrome (27 patients), Cushing's syndrome (30 patients), pheochromocytoma (11 patients), and Other tumors (26 patients). Antihypertensive therapy was eliminated or reduced for Conn's syndrome (75%), Cushing's syndrome (27%), pheochromocytoma (88%) and patients with Other tumors (54%). Clinical improvement was observed by 12 months for pheochromocytoma patients as compared with 35 to 45 months for the other groups (p < 0.05). Multivariate analysis showed that pheochromocytoma patients were more likely to experience improvement or cure than the Other tumor group (hazard ratio, 4.87; 95% confidence interval, 1.61-14.7). CONCLUSIONS: Laparoscopic adrenalectomy continues to be safe and efficacious for benign adrenal diseases. Although patients with functional tumors can expect improvement or cure, the time until improvement may be longer than previously recognized.
Authors:
B K Poulose; M D Holzman; O B Lao; E L Grogan; R E Goldstein
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Publication Detail:
Type:  Journal Article     Date:  2004-12-30
Journal Detail:
Title:  Surgical endoscopy     Volume:  19     ISSN:  1432-2218     ISO Abbreviation:  Surg Endosc     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-06-16     Completed Date:  2006-06-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8806653     Medline TA:  Surg Endosc     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  379-85     Citation Subset:  IM    
Affiliation:
Vanderbilt University School of Medicine, D-5203 Medical Center North, 1161 21st Avenue, Nashville, TN 37232, USA.
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MeSH Terms
Descriptor/Qualifier:
Adrenal Gland Diseases / complications,  surgery*
Adrenalectomy / adverse effects,  methods*,  statistics & numerical data*
Adult
Antihypertensive Agents / therapeutic use
Cohort Studies
Female
Follow-Up Studies
Humans
Hypertension / drug therapy,  etiology
Laparoscopy*
Male
Middle Aged
Multivariate Analysis
Postoperative Complications / epidemiology,  etiology
Questionnaires
Time Factors
Chemical
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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