| Lantus insulin overdose: a case report. | |
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MedLine Citation:
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PMID: 20493654 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background: Insulin glargine is a relatively new medication in the treatment of diabetes mellitus, and there have only been six case reports of overdoses in the literature with this specific insulin. Objectives: We present a unique case of insulin glargine overdose that presented with persistent hypoglycemia and required prolonged in-hospital treatment. Case Report: A 51-year-old woman with insulin-dependent diabetes and a history of suicide attempts by medication overdose presented to the Emergency Department the morning after she had self-administered 2700 units of her insulin glargine in an attempted suicide. She was treated with continuous intravenous dextrose infusion with liberal oral intake, and continued to have recurrent hypoglycemic episodes 96 h into her hospital stay. She was discharged on hospital day 5 after psychiatric clearance without any permanent complications. Conclusions: A single massive overdose of insulin glargine can present with prolonged hypoglycemia. Emergency physicians should have a low threshold for initiating continuous dextrose infusions and admitting these patients for frequent blood glucose and serum electrolyte monitoring, preferably in an intensive care setting. |
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Authors:
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Michael Lu; Pholaphat Charles Inboriboon |
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Publication Detail:
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Type: Journal Article Date: 2010-05-20 |
Journal Detail:
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Title: The Journal of emergency medicine Volume: 41 ISSN: 0736-4679 ISO Abbreviation: J Emerg Med Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8412174 Medline TA: J Emerg Med Country: United States |
Other Details:
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Languages: eng Pagination: 374-7 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Emergency Medicine, University of Rochester Medical Center, Rochester, New York. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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