Document Detail


Lanostane triterpenoids with cytotoxic activities from the fruiting bodies of Ganoderma hainanense.
MedLine Citation:
PMID:  23909866     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Twelve lanostane triterpenoids (1-12) including a new one 16α,26-dihydroxylanosta-8,24-dien-3-one (1) were isolated from the fruiting bodies of Ganoderma hainanense. The structure of the new compound was elucidated by 1D and 2D NMR and MS spectroscopic analyses. All isolates were evaluated for their cytotoxicities against human tumor cell lines K-562, SMMC-7721, and SGC-7901 and five compounds (1, 2, 5, 7, and 9) showed definite cytotoxicities against K-562 cell line. Meanwhile, compounds 2, 5, 7, and 9 exhibited cytotoxic activities against SMMC-7721 and SGC-7901 cell lines.
Authors:
Qing-Yun Ma; Ying Luo; Sheng-Zhuo Huang; Zhi-Kai Guo; Hao-Fu Dai; You-Xing Zhao
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-8-5
Journal Detail:
Title:  Journal of Asian natural products research     Volume:  -     ISSN:  1477-2213     ISO Abbreviation:  J Asian Nat Prod Res     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-8-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888334     Medline TA:  J Asian Nat Prod Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
a Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences , Haikou , 571101 , China.
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