Document Detail


Langerhans cell histiocytosis: two case reports in adults and review of the literature.
MedLine Citation:
PMID:  21128563     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Langerhans Cell histiocytosis is a rare proliferative histiocytic disorder in which pathologic Langerhans cells accumulate in a variety of organs. The clinical presentation, evolution and therapeutic options are highly variable. Because of its relative rarity and the broad clinical spectrum, the diagnosis of Langerhans cell histiocytosis is often delayed or missed. At present, many questions with respect to aetiology, pathogenesis and treatment remain unanswered. In the present article we want to raise the awareness of this rare disease in adults and its diversity by the means of two case reports. In addition, the clinical manifestations, diagnosis and the current management are reviewed.
Authors:
L Decoster; K De Braekeleer; C Bourgain; D Schallier
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Acta clinica Belgica     Volume:  65     ISSN:  1784-3286     ISO Abbreviation:  Acta Clin Belg     Publication Date:    2010 Sep-Oct
Date Detail:
Created Date:  2010-12-06     Completed Date:  2011-01-04     Revised Date:  2014-03-18    
Medline Journal Info:
Nlm Unique ID:  0370306     Medline TA:  Acta Clin Belg     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  345-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Histiocytosis, Langerhans-Cell / diagnosis*,  metabolism,  pathology,  radiography,  therapy
Humans
Immunohistochemistry
Male
Middle Aged
Prognosis
Young Adult

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