Document Detail


Langerhans cell histiocytosis revealed by painful hip: a case report.
MedLine Citation:
PMID:  19767229     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Langerhans cell histiocytosis is a rare disease in childhood. It has a very polymorphous clinical expression, ranging from a single bony disease to a multisystemic disease involving vital organs. Prognosis has been improved by use of chemotherapy. We report a 2-year-old girl with multifocal Langerhans cell histiocytosis of bone and skin, revealed by a pain of the left hip and a limp trailing from 2 months. The diagnosis has been established by histological exam. The patient received chemotherapy and steroids. Outcome was favourable over 6-month follow-up. Trailing limp should evoke diagnosis of Langerhans cell histiocytosis. Skin biopsy should be preferred to a bone biopsy because of its safety.
Authors:
Hammami Sabeur; B Meriem Chebil; B Ameur Karim; Hadded Samir; Gh??dira Leila; Hafsa Chiraz; Chouchane Slaheddine; Guediche Mohamed N??ji
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-09-19
Journal Detail:
Title:  Joint, bone, spine : revue du rhumatisme     Volume:  76     ISSN:  1778-7254     ISO Abbreviation:  Joint Bone Spine     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-26     Completed Date:  2010-01-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100938016     Medline TA:  Joint Bone Spine     Country:  France    
Other Details:
Languages:  eng     Pagination:  565-6     Citation Subset:  IM    
Affiliation:
Paediatric Department, Fattouma Bourguiba Hospital, Monastir, Tunisia. hamami_sabeur@yahoo.fr
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MeSH Terms
Descriptor/Qualifier:
Adrenal Cortex Hormones / therapeutic use
Female
Femur / pathology,  radiography
Functional Laterality
Hip Joint / pathology*,  radiography
Histiocytosis, Langerhans-Cell / drug therapy,  pathology*,  radiography
Humans
Infant
Magnetic Resonance Imaging
Osteosclerosis / radiography
Otitis / diagnosis
Pain / etiology
Treatment Outcome
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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