| Langerhans cell histiocytosis presenting as a limbal nodule in an adult patient. | |
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MedLine Citation:
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PMID: 15364252 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To report a case of Langerhans cell histiocytosis presenting as a limbal nodule. DESIGN: Observational case report. METHOD: A 26-year-old man presented with a superior limbal mass. On clinical examination, an infiltrative/neoplastic lesion was suspected, and a differential diagnosis of limbal amyloidosis, limbal fibrous histiocytoma, lymphoma, and juvenile xanthogranuloma was made. There was no other associated ocular or systemic abnormality. An excision biopsy was performed. RESULTS: The histopathology and immunohistochemical staining examination established the diagnosis of limbal Langerhans cell histiocytosis. CONCLUSION: To the best of our knowledge, this is an unusual presentation of Langerhans cell histiocytosis, and although rare, Langerhans cell histiocytosis should be included in the differential diagnosis of a limbal mass. |
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Authors:
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Tishu Saxena; Krishna Kumar; Seema Sen; Radhika Tandon |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of ophthalmology Volume: 138 ISSN: 0002-9394 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 2004 Sep |
Date Detail:
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Created Date: 2004-09-14 Completed Date: 2004-10-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: United States |
Other Details:
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Languages: eng Pagination: 508-10 Citation Subset: AIM; IM |
Affiliation:
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Cornea and Refractive Surgery Services, Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biological Markers / analysis Corneal Diseases / diagnosis*, metabolism Diagnosis, Differential Histiocytosis, Langerhans-Cell / diagnosis*, metabolism Humans Immunohistochemistry Limbus Corneae / metabolism, pathology* Male S100 Proteins / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/S100 Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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