Document Detail


Langerhans cell histiocytosis of the parietal bone with epidural and extracranial expansion - case report and a review of the literature.
MedLine Citation:
PMID:  20496290     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Langerhans cell histiocytosis is a rare neoplasm that belongs to the histiocytic and dendritic cell neoplasm group according to the 2008 WHO classification. It has been defined as neoplastic proliferation of Langerhans cells that express CD1a and S-100 proteins and have Birbeck granules on the ultrastructural examination. Clinical presentation and behaviour are heterogeneous and can range from a solitary lytic bone lesion with a favourable course to a fatal disseminated leukaemia-like form, with a wide spectrum of intermediate clinical presentations between these two extremes. Here, we present a case report of a solitary calvarial lesion in an adolescent boy along with a review of the literature. Presenting features, initial diagnostic evaluation and treatment protocol of a unifocal monosystemic calvarial location of LCH are presented.
Authors:
Anna Mosiewicz; Radosław Rola; Bozena Jarosz; Agnieszka Trojanowska; Tomasz Trojanowski
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Neurologia i neurochirurgia polska     Volume:  44     ISSN:  0028-3843     ISO Abbreviation:  Neurol. Neurochir. Pol.     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-05-24     Completed Date:  2010-07-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0101265     Medline TA:  Neurol Neurochir Pol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  196-203     Citation Subset:  IM    
Affiliation:
Katedra i Klinika Neurochirurgii i Neurochirurgii Dzieciecej, Uniwersytet Medyczny w Lublinie.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Cranial Fossa, Posterior
Histiocytosis, Langerhans-Cell / pathology*,  surgery*
Humans
Male
Neoplasm Invasiveness / pathology*
Parietal Bone*
Skull Neoplasms / pathology*,  surgery*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cerebral metastasis of a primary heart sarcoma.
Next Document:  Huge intradiploic epidermoid cyst.