| Lamotrigine-Induced Lupus-Like Syndrome: A Case Report and Literature Review. | |
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MedLine Citation:
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PMID: 23011169 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Lamotrigine, as a new generation anticonvulsant, has been widely used in treating epilepsy. It is also a mood stabilizer for bipolar disorder. Common adverse effects include nausea and vomiting, dyspepsia, insomnia, somnolence, and rash. However, drug-induced lupus (DIL) due to lamotrigine has been rarely reported. We report a case of lupus-like syndrome associated with lamotrigine. A 39-year-old male developed arthralgias and positive serum antinuclear antibody repeatedly with introductions of lamotrigine. The strong temporal relationship between the rheumatological features and drug exposure is illustrative of the disease course of DIL. Two hitherto reported lamotrigine-related DIL cases are compared with our case. |
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Authors:
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Richard Shek-Kwan Chang; Andrew J Cole |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-9-24 |
Journal Detail:
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Title: American journal of therapeutics Volume: - ISSN: 1536-3686 ISO Abbreviation: Am J Ther Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-9-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9441347 Medline TA: Am J Ther Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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1Epilepsy Service, Massachusetts General Hospital, Boston, MA 2Department of Neurology, Harvard Medical School, Boston, MA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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