Document Detail


Lamina repair and replacement to control laminectomy membrane formation in dogs.
MedLine Citation:
PMID:  1862416     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study examined the efficacy of lamina repair by the use of various techniques to prevent postlaminectomy scar formation in a canine system. Five-level noncontiguous laminectomies were performed on six adult canines. The most caudal (Site 1) was left uncovered and served as the control. Exposed dura at each of the remaining four levels was covered with one of the following: Site 2, free autogenous laminar bone graft; Site 3, polymethylmethacrylate; Site 4, Teflon-Proplast composite; Site 5, collagen gel. The dogs used in the study were killed 16 weeks after surgery. Three specimens were examined by plain roentgenography and computerized tomography, two specimens were examined histologically, and the remaining four specimens were graded according to scar volume and scar adherence, as detected during gross dissection of the postlaminectomy scar. No repair technique interfered with roentgenography evaluation. The least scar and fewest adhesions were present under the free bone graft repair site. The Teflon-Proplast composite and polymethylmethacrylate both limited the amount and adherence of scar. Collagen gel and control sites were indistinguishable in this study. It is concluded that lamina repair with a solid material covering exposed dura significantly reduces the formation of postlaminectomy membrane and scar.
Authors:
K J Lawson; J L Malycky; J L Berry; A D Steffee
Related Documents :
17262126 - Collagen analysis in human tooth germ papillae.
10743716 - A modified staining method for connective tissue in semi-thin histological sections of ...
19165766 - Preparation and in vivo evaluation of apatite/collagen packed composite by alternate im...
11506726 - Tissue-engineered fabrication of an osteochondral composite graft using rat bone marrow...
21906186 - Sinus bone formation and implant survival after sinus membrane elevation and implant pl...
17262126 - Collagen analysis in human tooth germ papillae.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Spine     Volume:  16     ISSN:  0362-2436     ISO Abbreviation:  Spine     Publication Date:  1991 Jun 
Date Detail:
Created Date:  1991-08-30     Completed Date:  1991-08-30     Revised Date:  2009-07-09    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S222-6     Citation Subset:  IM    
Affiliation:
Department of Orthopaedics, David Grant USAF Medical Center, Travis Air Force Base, California.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aluminum Oxide
Animals
Biocompatible Materials
Bone Transplantation
Cicatrix / prevention & control*
Dogs
Dura Mater / pathology
Gelatin Sponge, Absorbable
Laminectomy*
Lumbar Vertebrae / surgery*
Methylmethacrylates
Polytetrafluoroethylene
Postoperative Complications / prevention & control*
Proplast* / analogs & derivatives*
Tissue Adhesions / prevention & control*
Chemical
Reg. No./Substance:
0/Biocompatible Materials; 0/Methylmethacrylates; 0/Proplast; 0/proplast II; 1344-28-1/Aluminum Oxide; 9002-84-0/Polytetrafluoroethylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Clinical correlation between degenerative spine disease and dermatomal somatosensory-evoked potentia...
Next Document:  The importance of posterior epidural fat pad in lumbar central canal stenosis.