Document Detail

Lactoperoxidase activity in human milk and in saliva of newborn infants.
MedLine Citation:
PMID:  1140845     Owner:  NLM     Status:  MEDLINE    
Human milk and saliva from newborn infants were analyzed for their content of lactoperoxidase and thiocyanate. The activity of lactoperoxidase in infant saliva was variable but generally higher than that found in calf saliva. In contrast, the activity in human colostrum was low ( approximately 5%) compared with that found in cow's milk. The enzyme was resistant to gastric juice. Thiocyanate was demonstrated in infant saliva in concentrations about one-third of that in adult saliva. The amounts of lactoperoxidase and thiocyanate in infant saliva are quite sufficient to inhibit bacterial growth in in vitro systems. The importance of this system in vivo has not yet been demonstrated. The availability of this system to both newborn calves and humans (in calves provided largely by colostrum and in human babies by saliva) might be indirect evidence of its importance.
L Gothefors; S Marklund
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Infection and immunity     Volume:  11     ISSN:  0019-9567     ISO Abbreviation:  Infect. Immun.     Publication Date:  1975 Jun 
Date Detail:
Created Date:  1975-10-10     Completed Date:  1975-10-10     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0246127     Medline TA:  Infect Immun     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1210-5     Citation Subset:  IM    
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MeSH Terms
Colostrum / enzymology
Enzyme Inhibitors / analysis
Gastric Juice
Lactoperoxidase / analysis*
Leukocytes / enzymology
Milk / enzymology
Milk, Human / enzymology*
Peroxidases / analysis*
Saliva / enzymology*
Thiocyanates / analysis
Reg. No./Substance:
0/Enzyme Inhibitors; 0/Thiocyanates; EC 1.11.1.-/Lactoperoxidase; EC 1.11.1.-/Peroxidases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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