| Lactoferrin as a sensitive blood marker of neutrophil activation in normal pregnancies. | |
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MedLine Citation:
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PMID: 8582494 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To test lactoferrin as a marker of neutrophil activation during pregnancy. DESIGN: Cross-sectional study in normal pregnant (n = 100), nonpregnant (n = 11) and post partum women (n = 30). METHODS: Serum or plasma measurements of neutrophils, lactoferrin, vitamin C, vitamin E, lipid peroxide, elastase, C-reactive protein gamma-glutamyltranspeptidase, haptoglobin and osmotic fragility. RESULTS: During normal pregnancy all markers of neutrophil-activation increase. CONCLUSION: Neutrophil-activation compromises the antioxidant defense mechanism during normal pregnancy. |
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Authors:
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I Rebelo; F Carvalho-Guerra; L Pereira-Leite; A Quintanilha |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of obstetrics, gynecology, and reproductive biology Volume: 62 ISSN: 0301-2115 ISO Abbreviation: Eur. J. Obstet. Gynecol. Reprod. Biol. Publication Date: 1995 Oct |
Date Detail:
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Created Date: 1996-03-19 Completed Date: 1996-03-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0375672 Medline TA: Eur J Obstet Gynecol Reprod Biol Country: IRELAND |
Other Details:
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Languages: eng Pagination: 189-94 Citation Subset: IM |
Affiliation:
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Departamento de Bioquimica da Faculdade de Farmácia da Universidade do Porto, Portugal. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biological Markers / blood Cell Membrane / physiology Erythrocytes / pathology* Female Hematologic Tests Humans Inflammation / blood Lactoferrin / blood* Leukocyte Count Lipid Peroxidation / physiology* Neutrophil Activation / physiology* Oxidation-Reduction Pancreatic Elastase / blood* Pregnancy / blood* Reference Values Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Lactoferrin; EC 3.4.21.36/Pancreatic Elastase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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