| Lactocrine programming of female reproductive tract development: Environmental connections to the reproductive continuum. | |
| | |
MedLine Citation:
|
PMID: 22033320 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
For eutherian mammals a continuum of maternal support insures that development of progeny follows an optimal program. Beginning in utero, such support extends into the early neonatal period when bioactive factors are communicated from mother to offspring in colostrum/milk. Defined as lactocrine signaling, communication of milk-borne bioactive factors from mother to offspring as a consequence of nursing is important for development of somatic tissues, including the female reproductive tract (FRT). Data for the domestic pig indicate that lactocrine signaling contributes to the maternal continuum of factors that define the developmental program and determine the developmental trajectory of FRT tissues during early neonatal life. Both naturally occurring and manmade factors of environmental origin can be communicated to neonates in milk and affect development with lasting consequences. Here, evidence for lactocrine programming of FRT development and the potential for environmental endocrine disruption of this process are reviewed. |
| | |
Authors:
|
Frank F Bartol; Carol A Bagnell |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-10-19 |
Journal Detail:
|
Title: Molecular and cellular endocrinology Volume: - ISSN: 1872-8057 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
|
Created Date: 2011-10-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7500844 Medline TA: Mol Cell Endocrinol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011. Published by Elsevier Ireland Ltd. |
Affiliation:
|
Department of Anatomy, Physiology and Pharmacology, Cellular and Molecular Biosciences Program, Auburn University, Auburn, AL 36849, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Job stress and work schedules in relation to nurse obesity.
Next Document: Indoleamine 2,3-dioxygenase, a new prognostic marker in sentinel lymph nodes of melanoma patients.