| Lacticacidosis after short-term infusion of propofol for anaesthesia in a child with osteogenesis imperfecta. | |
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MedLine Citation:
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PMID: 14617125 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe the case of a 7-year-old boy with osteogenesis imperfecta, who underwent anaesthesia with propofol-fentanyl-nitrous oxide-suxamethonium for orthopaedic surgery of a distal femur fracture. He developed lacticacidosis after short-term propofol infusion (150 min, mean infusion rate 13.5 mg.kg-1.h-1) associated with a prolonged recovery time without serious haemodynamic changes. The highest lactate concentration was 9.2 mmol.l-1 at 160 min after discontinuation of propofol. There was no significant increase in body temperature. The boy fully recovered. |
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Authors:
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Clemens Kill; Andreas Leonhardt; Hinnerk Wulf |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Paediatric anaesthesia Volume: 13 ISSN: 1155-5645 ISO Abbreviation: Paediatr Anaesth Publication Date: 2003 Nov |
Date Detail:
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Created Date: 2003-11-17 Completed Date: 2004-04-22 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9206575 Medline TA: Paediatr Anaesth Country: France |
Other Details:
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Languages: eng Pagination: 823-6 Citation Subset: IM |
Affiliation:
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Department of Anaesthesiology and Intensive Care Medicine, Philipps-University, Marburg, Germany. killc@mailer.uni-marburg.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acidosis, Lactic
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blood,
chemically induced* Anesthesia, Intravenous / adverse effects* Anesthetics, Intravenous / adverse effects* Child Dose-Response Relationship, Drug Fasting / metabolism Femoral Fractures / complications, surgery Fentanyl / administration & dosage Hemodynamics / drug effects Humans Lactic Acid / blood Male Neuromuscular Nondepolarizing Agents / administration & dosage Osteogenesis Imperfecta / complications* Propofol / adverse effects* Succinylcholine / administration & dosage Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Intravenous; 0/Neuromuscular Nondepolarizing Agents; 2078-54-8/Propofol; 306-40-1/Succinylcholine; 437-38-7/Fentanyl; 50-21-5/Lactic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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