Document Detail


Lactic acidosis in a patient with acute leukemia.
MedLine Citation:
PMID:  6576875     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lactic acidosis is a rare but potentially fatal complication of acute leukemia. The terminal phase of acute leukemia in a 22-year-old woman, heralded by lactic acidosis, is described in order to focus attention on the occurrence of this metabolic disturbance in the absence of overt manifestations of acute leukemia. As reported in other cases, the lactic acidosis in our patient responded poorly to bicarbonate therapy but dramatically to antileukemic chemotherapy. The pathogenesis of the lactic acidosis is unclear but it may be the result of an undefined 'paraneoplastic' metabolic disturbance induced by the leukemic cells.
Authors:
L Grossman; R Holloway; M D'Costa; D Roncari; A Lazarovits; M Baker; D Pantalony
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical and investigative medicine. Médecine clinique et experimentale     Volume:  6     ISSN:  0147-958X     ISO Abbreviation:  Clin Invest Med     Publication Date:  1983  
Date Detail:
Created Date:  1983-10-28     Completed Date:  1983-10-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7804071     Medline TA:  Clin Invest Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  85-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acidosis / complications*,  diagnosis,  therapy
Acute Disease
Adolescent
Adult
Aged
Child
Child, Preschool
Female
Humans
Lactates*
Leukemia, Monocytic, Acute / complications*
Male
Middle Aged
Chemical
Reg. No./Substance:
0/Lactates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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