Document Detail

Lactic acid levels in patients with chronic obstructive pulmonary disease accomplishing unsupported arm exercises.
MedLine Citation:
PMID:  20348268     Owner:  NLM     Status:  MEDLINE    
Patients with chronic obstructive pulmonary disease (COPD) may suffer dyspnea when performing unsupported arm exercises (UAE). However, some factors related to the tolerance of the upper limbs during these exercises are not well understood. Our investigation was to determine if an unsupported arm exercise test in patients with COPD accomplishing diagonal movements increases lactic acid levels; also, we assessed the metabolic, ventilatory and cardiovascular responses obtained from the unsupported arm exercise test. The study used results of maximal symptom limited tests with unsupported arms and legs performed on 16 patients with COPD. In order to do the test, some metabolic, respiratory and cardiovascular parameters such as oxygen uptake (VO(2)), carbon dioxide production (VCO(2)), respiratory rate (RR), pulmonary ventilation (VE), heart rate (HR) and blood pressure (BP) were measured during the exercise tests. Furthermore, blood lactate concentration was measured during the arm test. We detected a significant increase in the mean blood lactate concentration, VO(2), VCO(2), VE and RR from the resting to the peak phase of the UAE test. The mean values of VO(2), VCO(2) and VE obtained at the peak of the UAE test corresponded to 52.5%, 50.0% and 61.2%, respectively, of the maximal values obtained at the peak of the leg exercise test. In comparison, the mean heart rate and systolic arterial blood pressure were significantly lower at the peak of the UAE test than at the peak leg exercise test and corresponded to 76.2% and 83.0%, respectively. Unsupported incremental arm exercises in patients with COPD increases blood lactic acid levels.
Gérson F de Souza; Antonio A M Castro; Marcelo Velloso; Camille R Silva; José R Jardim
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-03-26
Journal Detail:
Title:  Chronic respiratory disease     Volume:  7     ISSN:  1479-9731     ISO Abbreviation:  Chron Respir Dis     Publication Date:  2010  
Date Detail:
Created Date:  2010-05-18     Completed Date:  2010-10-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101197408     Medline TA:  Chron Respir Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  75-82     Citation Subset:  IM    
Pulmonary Rehabilitation Center, Federal University of São Paulo, Unifesp, Brazil.
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MeSH Terms
Acidosis, Lactic / blood,  etiology*
Blood Pressure / physiology
Exercise / physiology*
Exercise Test / methods*
Exercise Tolerance / physiology*
Follow-Up Studies
Forced Expiratory Volume / physiology
Heart Rate / physiology
Lactic Acid / blood*
Oxygen Consumption / physiology
Pulmonary Disease, Chronic Obstructive / blood*,  diagnosis,  physiopathology
Severity of Illness Index
Reg. No./Substance:
50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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