Document Detail


Lactational programming? Mother's milk energy predicts infant behavior and temperament in rhesus macaques (Macaca mulatta).
MedLine Citation:
PMID:  20162547     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There are many aspects of "mothering" that may provide information to the mammalian infant about environmental conditions during critical periods of development. One essential element of mothering involves the quantity and quality of milk that mothers provide for their infants, but little is known about the consequences of variation in milk production. Mother's milk may affect infant behavior by contributing to brain development and to the development of behavioral dispositions. Here we present the first evidence for any mammal that natural variation in available milk energy (AME) from the mother is associated with later variation in infant behavior and temperament in rhesus macaques (Macaca mulatta, N=59). In the early postnatal period, heavier mothers with more reproductive experience produced greater AME, which is the product of milk energy density (kcal/g) and milk yield (g). Moreover, infants whose mothers produced greater AME in the early postnatal period showed higher activity levels and greater confidence in a stressful setting later in infancy. Our results suggest that the milk energy available soon after birth may be a nutritional cue that calibrates the infant's behavior to environmental or maternal conditions. These data provide new insight into potential mechanisms for the development of behavior and temperament and illuminate new directions for investigating maternal effects, nutritional programming, and developmental plasticity.
Authors:
Katie Hinde; John P Capitanio
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  American journal of primatology     Volume:  72     ISSN:  1098-2345     ISO Abbreviation:  Am. J. Primatol.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-04-30     Completed Date:  2010-08-03     Revised Date:  2014-09-22    
Medline Journal Info:
Nlm Unique ID:  8108949     Medline TA:  Am J Primatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  522-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Animals, Suckling / physiology*,  psychology
Behavior, Animal / physiology*
Energy Metabolism
Female
Lactation
Macaca mulatta / physiology*,  psychology
Male
Milk / chemistry,  metabolism*
Nutritional Status
Nutritive Value
Temperament*
Grant Support
ID/Acronym/Agency:
R24 OD010962/OD/NIH HHS; R24 RR019970/RR/NCRR NIH HHS; R24 RR019970-01/RR/NCRR NIH HHS; RR000169/RR/NCRR NIH HHS; RR019970/RR/NCRR NIH HHS
Comments/Corrections

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