Document Detail

Lactation: some cardiovascular and metabolic consequences, and the mechanisms of lactose and ion secretion into milk.
MedLine Citation:
PMID:  801809     Owner:  NLM     Status:  MEDLINE    
Lactation causes increases in mammary blood flow, gastrointestinal blood flow and cardiac output in the rat, and the suckling-induced release of lactogenic anterior pituitary hormones probably causes these changes, directly or indirectly. Metabolic requirements of lactation in women are similar to those in other animals not artificially selected for a high milk yield but the physiological control of the relationship between milk secretion and nutrient availability is not well understood. The unusual composition of the aqueous phase of human milk (rich in lactose but poor in sodium and potassium ions) can be explained by the same basic mechanisms for secretion of lactose and ions as operate in other animals but with quantitative differences.
M Peaker
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Ciba Foundation symposium     Volume:  -     ISSN:  0300-5208     ISO Abbreviation:  Ciba Found. Symp.     Publication Date:  1976  
Date Detail:
Created Date:  1978-05-24     Completed Date:  1978-05-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0356636     Medline TA:  Ciba Found Symp     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  87-101     Citation Subset:  IM    
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MeSH Terms
Blood Circulation
Breast / physiology
Cardiac Output
Chlorides / secretion
Digestive System / blood supply
Lactose / secretion
Mammary Glands, Animal / blood supply,  physiology
Milk / metabolism*
Milk, Human / metabolism*
Models, Biological
Potassium / secretion
Sodium / secretion
Species Specificity
Sucking Behavior
Reg. No./Substance:
0/Chlorides; 63-42-3/Lactose; 7440-09-7/Potassium; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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