Document Detail

Lactate transport across the bovine rumen epithelium in vitro.
MedLine Citation:
PMID:  9123981     Owner:  NLM     Status:  MEDLINE    
The in vitro transport of L-lactate across rumen epithelium was found to be a passive, mass-action regulated diffusion, and no saturable transport mechanisms were involved at concentrations from 2-20 mmol/L. During this increase in L-lactate concentrations the epithelial resistance and potential difference increased significantly, indicating an epithelial change towards a more tight epithelium. The net sodium transport was significantly reduced by 45% at 20 mmol/L lactate as compared to lactate free conditions.
P D Møller; L Diernaes; J Sehested; J Hyldgaard-Jensen; E Skadhauge
Publication Detail:
Type:  In Vitro; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Zentralblatt für Veterinärmedizin. Reihe A     Volume:  44     ISSN:  0514-7158     ISO Abbreviation:  Zentralbl Veterinarmed A     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-04-24     Completed Date:  1997-04-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0331323     Medline TA:  Zentralbl Veterinarmed A     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  31-8     Citation Subset:  IM    
Department of Animal Physiology, Royal Veterinary and Agricultural University, Copenhagen, Denmark.
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MeSH Terms
Biological Transport / drug effects,  physiology
Cattle / metabolism*,  physiology
Dose-Response Relationship, Drug
Epithelium / metabolism,  physiology
Lactates / metabolism,  pharmacokinetics*,  pharmacology
Regression Analysis
Rumen / metabolism*,  physiology
Sodium / metabolism,  pharmacokinetics
Reg. No./Substance:
0/Lactates; 7440-23-5/Sodium

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