| Lactate response to short term exercise with elevated starting levels. | |
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MedLine Citation:
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PMID: 20414670 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A model that describes the blood lactate concentration (BLC) dynamics [BLC(t)] of a Wingate Anaerobic Test (WAnT) as a function of (a) BLC at the start of exercise (BLC(0)), (b) extra-vascular increase in lactate (A), (c) two corresponding velocity constants of appearance (k (1)) and disappearance (k (2)) of lactate into and out of the blood requires that BLC(0) is equal to resting BLC (BLC(rest)). We developed a model that considers an elevated BLC(0). 19 males performed WAnTs with warm-ups increasing (p < 0.001) BLC(0). The goodness of each individual fit improved (p < 0.05) if the difference between BLC(rest) and BLC(0) (DeltaBLC) was higher than 1.0 mmol l(-1). All differences between old and new model (p < 0.05) in A, k (1) and k (2) were interrelated with and increased with DeltaBLC (p < 0.05). The new model well describes BLC(t) and prevents substantial errors concerning lactate generation and dynamics if BLC(0) is elevated by more than 1.0 mmol l(-1). |
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Authors:
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Ralph Beneke; Anna Wittekind; Monika Mühling; Imogen Bleif; Renate M Leithäuser |
Publication Detail:
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Type: Comparative Study; Journal Article Date: 2010-04-23 |
Journal Detail:
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Title: European journal of applied physiology Volume: 110 ISSN: 1439-6327 ISO Abbreviation: Eur. J. Appl. Physiol. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-12 Completed Date: 2010-12-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100954790 Medline TA: Eur J Appl Physiol Country: Germany |
Other Details:
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Languages: eng Pagination: 215-8 Citation Subset: IM |
Affiliation:
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Department of Biological Sciences, Centre for Sports and Exercise Science, University of Essex, Wivenhoe Park, Colchester, CO4 3SQ, UK. rbeneke@essex.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biological Markers / blood Exercise* Exercise Test Humans Kinetics Lactic Acid / blood* Male Models, Biological* Muscle Contraction* Muscle, Skeletal / metabolism* Recovery of Function Up-Regulation Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 50-21-5/Lactic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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