Document Detail

Lactate and pyruvate as fetal metabolic substrates.
MedLine Citation:
PMID:  1272628     Owner:  NLM     Status:  MEDLINE    
Lactate and pyruvate concentration differences across the fetal umbilical circulation and the maternal uterine circulation were measured in a chronic sheep preparation. Significant gains in lactate in both the fetal and maternal circulations were observed. The lactate taken up by the fetus would account for 32% of fetal oxygen consumption if oxidized. There was no significant change in pyruvate concentration across the fetal umbilical circulation; however, pyruvate was gained by maternal uterine blood.
V C Char; R K Creasy
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Pediatric research     Volume:  10     ISSN:  0031-3998     ISO Abbreviation:  Pediatr. Res.     Publication Date:  1976 Apr 
Date Detail:
Created Date:  1976-08-02     Completed Date:  1976-08-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0100714     Medline TA:  Pediatr Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  231-4     Citation Subset:  IM    
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MeSH Terms
Carbohydrate Metabolism
Fetal Blood / analysis
Fetus / metabolism*
Lactates / blood,  metabolism*
Maternal-Fetal Exchange
Models, Biological
Oxygen Consumption
Pyruvates / blood,  metabolism*
Reg. No./Substance:
0/Lactates; 0/Pyruvates

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