| Lactate provocation of panic attacks in depressed outpatients. | |
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MedLine Citation:
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PMID: 3217465 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Forty-seven nonmelancholic depressed outpatients were infused with sodium lactate to explore the relationship between history of panic attacks and lactate-induced panic. Lactate panic was rated without knowledge of history of panic. Fifteen of 29 patients (52%) with a history of spontaneous panic experienced panic attacks in response to lactate. Only 1 of 18 patients (6%) without a history of spontaneous panic experienced a lactate-induced panic attack--a highly significant difference. The likelihood of lactate panic was related to frequency of spontaneous panic attacks. The implications of these findings for understanding the relationship of panic attacks and depression are discussed. |
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Authors:
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P J McGrath; J W Stewart; M R Liebowitz; J M Markowitz; F M Quitkin; D F Klein; J M Gorman |
Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Psychiatry research Volume: 25 ISSN: 0165-1781 ISO Abbreviation: Psychiatry Res Publication Date: 1988 Jul |
Date Detail:
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Created Date: 1989-03-08 Completed Date: 1989-03-08 Revised Date: 2008-04-17 |
Medline Journal Info:
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Nlm Unique ID: 7911385 Medline TA: Psychiatry Res Country: IRELAND |
Other Details:
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Languages: eng Pagination: 41-7 Citation Subset: IM |
Affiliation:
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New York State Psychiatric Institute, NY 10032. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Anxiety Disorders / psychology Depressive Disorder / psychology* Fear* / drug effects Humans Infusions, Intravenous Lactates / diagnostic use* Lactic Acid Middle Aged Panic* / drug effects Psychological Tests |
| Grant Support | |
ID/Acronym/Agency:
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5R01 MH-39143/MH/NIMH NIH HHS; MH-30906/MH/NIMH NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Lactates; 50-21-5/Lactic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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