Document Detail

Lactate concentration in plasma and red blood cells during incremental exercise.
MedLine Citation:
PMID:  11071046     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to investigate the distribution of lactate in plasma and red blood cells (RBC) in capillary blood during and after incremental exercise. We measured capillary plasma lactate and whole blood lactate of 10 subjects during incremental treadmill running and the first 20 min of recovery. To minimize lactate exchange from plasma to RBC between sampling and analysis, a recently developed rapid plasma separation method was used. RBC lactate was calculated. The RBC/plasma lactate concentration ratio decreased from 1.0 (0.85-1.28) before to 0.37 (0.25-0.45) after exhaustive exercise (plasma lactate 15.9 (12.2-19.5)mmol x I(-1), RBC lactate 4.8 (4.0-7.0) mmol x 1(-1)), thus showing that capillary plasma lactate increased much more rapidly than intracellular lactate during incremental exercise. In the first 5 minutes of recovery intracellular lactate still rose while plasma lactate already declined. Then both decreased while the concentration ratio as well as the absolute concentration gradient remained nearly constant (ratio 20 min after exercise termination: 0.43 (0.19-0.54).
A Hildebrand; W Lormes; J Emmert; Y Liu; M Lehmann; J M Steinacker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of sports medicine     Volume:  21     ISSN:  0172-4622     ISO Abbreviation:  Int J Sports Med     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2001-02-23     Completed Date:  2001-03-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  463-8     Citation Subset:  IM    
Abt Sport- und Rehabilitationsmedizin, Universitätsklinikum Ulm, Germany.
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MeSH Terms
Erythrocytes / chemistry*
Exercise / physiology*
Lactates / blood*
Reg. No./Substance:

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