Document Detail


Lack of utility of specific immunoglobulin G antibody avidity for serodiagnosis of reactivated toxoplasmosis in immunocompromised patients.
MedLine Citation:
PMID:  10882677     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The avidities of Toxoplasma-specific immunoglobulin G serum antibodies were measured in immunocompromised patients presenting with cerebral or extracerebral toxoplasmosis and/or serological reactivation. Since avidity remained high and stable in 39 of 40 patients with toxoplasmosis and 27 of 28 patients with serological reactivation, we conclude that this test cannot help diagnose toxoplasmosis in these patients.
Authors:
B Mechain; Y J Garin; F Robert-Gangneux; J Dupouy-Camet; F Derouin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and diagnostic laboratory immunology     Volume:  7     ISSN:  1071-412X     ISO Abbreviation:  Clin. Diagn. Lab. Immunol.     Publication Date:  2000 Jul 
Date Detail:
Created Date:  2000-09-12     Completed Date:  2000-09-12     Revised Date:  2010-09-14    
Medline Journal Info:
Nlm Unique ID:  9421292     Medline TA:  Clin Diagn Lab Immunol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  703-5     Citation Subset:  IM    
Affiliation:
Laboratoire de Parasitologie-Mycologie, Hôpital Saint-Louis, 75475 Paris Cedex 10, France.
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MeSH Terms
Descriptor/Qualifier:
Animals
Antibodies, Protozoan / analysis,  immunology*
Antibody Affinity
Antibody Specificity
Humans
Immunocompromised Host*
Immunoglobulin G / analysis,  immunology
Opportunistic Infections / diagnosis,  immunology
Sensitivity and Specificity
Serologic Tests
Toxoplasma / immunology*
Toxoplasmosis / diagnosis*,  immunology*
Chemical
Reg. No./Substance:
0/Antibodies, Protozoan; 0/Immunoglobulin G
Comments/Corrections

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