| Lack of transplacental infection with scrub typhus organisms in laboratory mice. | |
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MedLine Citation:
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PMID: 6424486 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Female mice were inoculated with either a virulent or avirulent strain of Rickettsia tsutsugamushi before (1 month and 1 week) or after (approximately 10 days) impregnation. From each group, two pregnant mothers were killed on day 20 post-impregnation, and fetuses and placentas were examined for rickettsiae. Organisms were isolated from 80% of placentas but not from the fetuses. Immediately following parturition, litters from 50% of the infected mothers were exchanged with litters from uninfected mothers. In all cases, no scrub typhus rickettsiae were found in the litters examined on days 1, 7, and 30 postpartum, and no antibody was found in sera collected 1 and 2 months postpartum. |
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Authors:
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A Shirai; T C Chan; E Gan; M G Groves |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: The American journal of tropical medicine and hygiene Volume: 33 ISSN: 0002-9637 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 1984 Mar |
Date Detail:
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Created Date: 1984-05-10 Completed Date: 1984-05-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 285-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antibodies, Bacterial / analysis Brain / microbiology Female Fetal Blood / immunology Fetus / microbiology Liver / microbiology Maternal-Fetal Exchange* Mice Orientia tsutsugamushi / immunology, isolation & purification* Placenta / microbiology* Pregnancy Pregnancy Complications, Infectious* Scrub Typhus / transmission* Spleen / microbiology |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Bacterial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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