| Lack of a relationship between colony-forming efficiency and surviving fraction at 2 Gy. | |
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MedLine Citation:
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PMID: 2023996 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The relationship between in vitro radiation sensitivity and colony-forming efficiency has been examined for primary human tumors of the cervix, colorectum, and lymph gland. Tumors were cultured using the Courtenay-Mills soft agar clonogenic assay and radiosensitivity was assessed as surviving fraction at 2 Gy. There was no correlation between colony-forming efficiency and surviving fraction at 2 Gy, giving confidence to the use of surviving fraction at 2 Gy as a predictor of clinical outcome. |
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Authors:
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C M West; S E Davidson; C Pool; R D James; P F Schofield |
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Publication Detail:
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Type: In Vitro; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Radiation research Volume: 126 ISSN: 0033-7587 ISO Abbreviation: Radiat. Res. Publication Date: 1991 May |
Date Detail:
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Created Date: 1991-06-06 Completed Date: 1991-06-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401245 Medline TA: Radiat Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 260-3 Citation Subset: IM; S |
Affiliation:
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Cancer Research Campaign Department of Radiobiology, Paterson Institute for Cancer Research, Manchester, United Kingdom. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cell Survival
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radiation effects* Cesium Radioisotopes Colonic Neoplasms / pathology, radiotherapy Female Gamma Rays Humans Neoplasms / pathology*, radiotherapy Rectal Neoplasms / pathology, radiotherapy Tumor Stem Cell Assay* Uterine Cervical Neoplasms / pathology, radiotherapy |
| Chemical | |
Reg. No./Substance:
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0/Cesium Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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