Document Detail


Lack of effect of ouabain on sodium transport across the rat placenta.
MedLine Citation:
PMID:  573457     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The umbilical vascular bed of the rat placenta was perfused in situ. Ouabain (10(-4)M) in the perfusion fluid had no effect on the unidirectional flux of Na+ from the maternal (electrically negative) to the foetal (electrically positive) side of the placenta, or on the transplacental potential difference. This was taken to indicate that there is no significant active transport of Na+ across the placenta of the rat.
Authors:
J Stulc; B Stulcová
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pflügers Archiv : European journal of physiology     Volume:  381     ISSN:  0031-6768     ISO Abbreviation:  Pflugers Arch.     Publication Date:  1979 Jul 
Date Detail:
Created Date:  1979-11-28     Completed Date:  1979-11-28     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0154720     Medline TA:  Pflugers Arch     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  79-81     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Transport, Active / drug effects
Female
Maternal-Fetal Exchange / drug effects*
Ouabain / pharmacology*
Pregnancy
Rats
Sodium / metabolism*
Chemical
Reg. No./Substance:
630-60-4/Ouabain; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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